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Immunology

Image: The Cobas Е 801 Analyzer analytical unit is a high throughput immunochemistry module that performs a broad range of heterogeneous immunoassay tests (Photo courtesy of Dialogue Diagnostics LLC)

CSF Immunoassays Aid Diagnosis of Early Alzheimer’s Disease

The pathological processes underlying Alzheimer’s disease (AD) begin many years before clinical presentation. Ongoing drug discovery efforts in AD focus on developing disease-modifying treatments aiming to delay onset or progression of dementia and must be initiated early in the disease process. More...
21 Dec 2022
Image: A T cell receptor that recognizes a human protein fragment (left) is remarkably similar to one that recognizes a bacterial protein fragment (right), and to two receptors capable of recognizing both human and bacterial protein fragments (middle) (Photo courtesy of Washington University School of Medicine)

Autoimmunity-Associated T Cell Receptors Recognize HLA-Variant-Bound Peptides

The immune response in autoimmune disease recapitulates that of responses directed against infection, except that self-antigens are, or become, the target of the adaptive immune system. These self-antigens may drive a process that is localized within a specific organ, such as the thyroid gland (Grave’s disease, Hashimoto’s thyroiditis) or brain (multiple sclerosis). More...
13 Dec 2022
Image: Endomyocardial biopsy showing lymphocytic myocarditis (Photo courtesy of Marion University)

Blood Test for Myocarditis Detects Heart Inflammation

Myocarditis is a difficult condition to diagnose. Symptoms include a temperature, fatigue, chest pain and shortness of breath, which can all be easily mistaken for other conditions. The gold standard method for diagnosis is a heart biopsy, an expensive, invasive, and risky procedure which can sometimes still miss signs of the condition. More...
05 Dec 2022
Image: Antiphospholipid Antibodies Evaluated in Autoimmune Thyroid Diseases (Photo courtesy of VisitHealth limited)

Antiphospholipid Antibodies Evaluated in Autoimmune Thyroid Diseases

Autoimmune thyroid diseases (AITD) is the most common organ-specific autoimmune disease, mainly caused by genetic predisposition, environmental factors and dysfunction in the microbiome. More...
29 Nov 2022
Image: Enzyme-linked immunosorbent assay were used to measure serum levels of IL-37, IL-38, and Vitamin D (Photo courtesy of MyBioSource Inc)

Interleukins and Vitamin D Evaluated in Women With Graves' Disease

Graves' disease (GD), an autoimmune disorder specific to the thyroid, is the leading cause of hyperthyroidism due to an enlarged and hyperactive thyroid gland, associated with extra-thyroidal manifestations, such as orbitopathy and pretibial myxedema. More...
23 Nov 2022
Image: Infections by Epstein-Barr virus usually cause no symptoms, but a growing body of evidence suggests it plays a role in multiple sclerosis (Photo courtesy of Kateryna Kon, MD, PhD)

More Evidence for Epstein - Barr virus' Role in MS Found

The Epstein-Barr virus (EBV) is a common virus that causes glandular fever (infectious mononucleosis), usually in teenagers and young adults. It has been proposed as a possible trigger for multiple sclerosis, and is also implicated in some cancers. More...
14 Nov 2022
Image: Immune Reaction to Gut Bacterium May Trigger Rheumatoid Arthritis (Photo courtesy of Everyday Health)

Immune Reaction to Gut Bacterium May Trigger Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune condition in which the immune system attacks the tissues of the joints, especially in the knees, hands, and wrists. This causes inflammation and painful swelling. More...
31 Oct 2022
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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