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Immunology

Image: Indirect hemagglutination test for the detection of antibodies against Trypanosoma cruzi (Photo courtesy of Wiener lab. Group).

Immunoassays Compared to Improve Diagnosis of Chagas Disease

Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is a vector-borne infection of significant public health concern in Latin America, where nearly six million people are infected and 70 million are at risk of infection. More...
26 Oct 2019
Image: The cobas e 601 is a fully automated analyzer that uses a patented electrochemiluminescence (ECL) technology for immunoassay analysis (Photo courtesy of Roche Diagnostics).

Handling Procedures Affect Interleukin 6 Levels in Samples

Interleukin‐6 (IL‐6), a pleiotropic cytokine, is released by a variety of cell types such as immune cells, endothelial cells, and even certain tumor cells. It is a classic proinflammation cytokine which exhibits broad‐ranging biological activities by involved in the intricate cellular communication. More...
26 Oct 2019
Image: The VACUETTE Venous K2EDTA blood collection tubes were found the most suitable for the pre-analytical conditions for serotonin assays (Photo courtesy of Greiner Bio-One).

Pre-Analytical Protocols Compared for Serotonin Quantification

Serotonin (5-hydroxytryptamine) is an important neurotransmitter and neuromodulator, which affects many neurophysiological processes, mood and cognition, regulates motility and sensibility in the bowel, and has an essential role in regulating blood pressure. More...
24 Oct 2019
Image: The PATHFAST compact benchtop automatic immunoassay analyzer (Photo courtesy of LSI Medience).

Presepsin Concentrations Correlate with Kidney Function Decline

Sepsis is an important public health problem with more than 750,000 patients reported yearly in the USA with similar figures in Europe. Sepsis continues to be a challenge for practitioners, as sepsis mortality rates are still high despite new antimicrobial and resuscitation agents. More...
24 Oct 2019
Image: A multiple sclerosis chip (MS chip) was designed using the Illumina iSelect platform (Photo courtesy of Illumina).

Immune Processes Linked to Multiple Sclerosis Genetics

Multiple sclerosis (MS) is an autoimmune inflammatory degenerative disease of the central nervous system that often starts in young adulthood and affects 2.3 million individuals worldwide. While prior genetic studies have implicated the adaptive immune system in the disease, in particular T cells, much of the genetic architecture of MS has remained unknown. More...
17 Oct 2019
Image: Myeloperoxidase positive staining from a patient with acute myeloid leukemia (Photo courtesy of Monika Nema, MD).

Specific Cytokines Are Significant Biomarkers for AML

Acute myeloid leukemia is a hematopoietic neoplasm derived from early progenitor myeloid cells; it is characterized by clonal expansion of myeloblasts, which are immature myeloid progenitors that accumulate in the bone marrow (BM). More...
16 Oct 2019
Image: The NovoCyte flow cytometer (Photo courtesy of ACEA Bio).

Blood Monocyte Functions Altered in Parkinson's Disease

Parkinson's disease is characterized by the slow degeneration of the neurons in brain due to the abnormal accumulation of a protein called alpha-synuclein. This leads to the patients shaking and then to the slow, stiff movements which many people associate with the disease. More...
15 Oct 2019
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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