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Immunology

Image: A histopathology of nodular glomerulosclerosis in a patient with long-standing diabetes mellitus. Note the markedly thickened arteriole at the lower right, which is typical for the hyaline arteriolosclerosis that is seen in diabetic kidneys as well (Photo courtesy of University of Utah).

Collagen Biomarkers Clarify Prognosis of Diabetic Renal Complications

Type 1 diabetes, once known as juvenile diabetes or insulin-dependent diabetes, is a chronic condition in which the pancreas produces little or no insulin. Insulin is a hormone needed to allow sugar (glucose) to enter cells to produce energy. More...
24 Jul 2019
Image: An immunohistochemical staining IL-17A expression in (A) M. mycetomatis, and (B) S. somaliensis. IL-17A staining was seen as a brown cytoplasmic staining in cells (Photo courtesy of University of Khartoum).

Immune Molecules Expressed Inside Mycetoma Lesions

Mycetoma is a persistent, progressive granulomatous inflammatory disease caused either by fungi or by bacteria. Characteristic of this disease is that the causative agents organize themselves in macroscopic structures called grains. These grains are surrounded by a massive inflammatory reaction. More...
24 Jul 2019
DIASOURCE (A Biovendor Company)
Image: An immunoglobulin G (IgG)-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis (Photo courtesy of Institut Pasteur).

Immunoglobulins and Neutrophils Play Unexpected Role in Anaphylaxis

Anaphylaxis may be brought about by various substances, including drugs (antibiotics or neuromuscular blocking agents), food and insect venom. Anaphylaxis is a hyperacute allergic reaction caused by an inappropriate immune response following the introduction of a usually harmless antigen into the body. More...
23 Jul 2019
Image: A scanning electron micrograph (SEM) of infectious particles of the avian H7N9 virus emerging from a cell (Photo courtesy of Medical Xpress).

T Cell Antibody and Memory in H7N9 Survivors Characterized

Avian influenza A (H7N9) is a subtype of influenza viruses that have been detected in birds in the past. This particular A (H7N9) virus had not previously been seen in either animals or people until it was found in March 2013 in China. More...
19 Jul 2019
Image: Defective Selection of Autoreactive B Cells seen in Systemic Lupus Erythematosus (Photo courtesy of Sebastian Kaulitzki).

Early B Cell Differentiation Activation Seen in Lupus

In people with systemic lupus erythematosus, their B cells, part of the immune system, are abnormally activated. They produce antibodies that react against their own tissues, causing a variety of symptoms, such as fatigue, joint pain, skin rashes and kidney problems. More...
17 Jul 2019
Image: QuantiFERON-TB Gold (QFT) is an innovative blood test that measures the cell-mediated immune response of Mycobacterium tuberculosis infected individuals (Photo courtesy of Qiagen).

TB Tests May Not Detect Infection in Exposed Individual

Mycobacterium tuberculosis is the leading infectious cause of death worldwide Exposure to M. tuberculosis results in heterogeneous clinical outcomes including primary progressive tuberculosis (TB) and latent tuberculosis infection (LTBI). More...
17 Jul 2019
Image: An example of an ELISA test kit designed for quantitative determination of the concentration of human interleukin 6 (IL-6) in serum and plasma (Photo courtesy of Thermo Fisher Scientific).

Blood Biomarkers Help Predict Recovery Time after Concussion

A study of high school and college football players suggests that biomarkers in the blood may have potential use in identifying which players are more likely to need a longer recovery time after concussion. More...
17 Jul 2019
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.

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