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Immunology

Image: The Leptospira ELISA IgM assay (Photo courtesy of Panbio)

Leptospira IgM ELISA Evaluated Among Outpatients in Southern Asia

Leptospirosis is a widespread but neglected zoonotic disease caused by a bacterium of the genus Leptospira. Leptospirosis contributes to approximately 48,000 annual deaths globally, with 500,000 cases estimated worldwide, and remains a major public health concern in tropical and subtropical regions. Weil’s disease is a severe form of leptospirosis. More...
26 May 2021
Image: The Beckman Coulter AcT Diff automatic cell counter (Photo courtesy of Beckman Coulter)

Innate Lymphoid Cells Analyzed at the Maternal-Fetal Interface

Preterm birth (PTB) is one of the major causes of neonatal morbidity and mortality worldwide. It is commonly accepted that the act of giving birth is the final step in a proinflammatory signaling cascade, orchestrated by an intrauterine milieu coupled to hormonal cues. More...
26 May 2021
Image: The CHEMOSTAR Touch ECL & Fluorescence Imager (Photo courtesy of INTAS)

Non‐Invasive Urine Markers Differentiate Renal Cancer from Oncocytoma

Clear cell renal cell carcinoma, (ccRCC), is a type of kidney cancer. Clear cell renal cell carcinoma is also called conventional renal cell carcinoma. Clear cell renal cell carcinoma is named after how the tumor looks under the microscope. More...
25 May 2021
Image: The Elecys S100 Assay, an electro-chemiluminescence immunoassay (ECLIA) for the in vitro quantitative determination of S100 in human serum (Photo courtesy of Roche Diagnostics)

Plasma-Based S100B Testing for Management of Traumatic Brain Injury

Traumatic brain injury (TBI) usually results from a violent blow or jolt to the head or body. An object that penetrates brain tissue, such as a bullet or shattered piece of skull, also can cause traumatic brain injury. Mild traumatic brain injury may affect the brain cells temporarily. More...
24 May 2021
Image: Schematic diagram of How Human Microbiota Flagellins Drive Adaptive Immune Responses in Crohn’s Disease (Photo courtesy of University of Alabama at Birmingham)

Human Microbiota Flagellins Drive Adaptive Immune Responses in Crohn’s Disease

Crohn's disease and ulcerative colitis, another type of inflammatory bowel disease (IBD), are characterized by dysregulated adaptive immune responses to the microbiota in genetically susceptible individuals, but the human specificity of these responses had so far been largely undefined. More...
20 May 2021
Image: Photomicrograph of Mycobacterium tuberculosis - Ziehl-Neelsen Acid-Fast Stains bacteria red (Photo courtesy of Rockefeller University)

Potential Immune Markers Found for Active Tuberculosis

Tuberculosis (TB) is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. Tuberculosis generally affects the lungs, but can also affect other parts of the body. Most infections show no symptoms, in which case it is known as latent tuberculosis. About 10% of latent infections progress to active disease which, if left untreated, kills about half of those affected. More...
18 May 2021
Image: Multiomic prediction of time to labor from biomarkers in maternal blood (Photo courtesy of STELZER ET AL.)

Maternal Multiomic Changes Could Predict Onset of Labor

Currently, predictions of when labor will start are imprecise and based on gestational age and an average pregnancy length of 40 weeks, even though the onset of labor between week 37 and 42 of pregnancy is considered normal. Having a better idea of when labor may arrive could help with planning and managing medical concerns like fetal lung maturation. More...
18 May 2021
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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