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Hematology

Image: Bone marrow aspirate from a patient with classical Hodgkin Lymphoma with large multinucleated Reed-Sternberg cells. “Hodgkin cells” are mononuclear while “Reed-Sternberg” cells are multinucleate forms (Photo courtesy of Nidia P. Zapata, MD and Espinoza-Zamora Ramiro)

Checkpoint Protein Expression in Tumor Microenvironment Defines Prognosis of Hodgkin Lymphoma Patients

In Hodgkin lymphoma, B-lymphocytes start to multiply in an abnormal way and begin to collect in certain parts of the lymphatic system, such as the lymph nodes (glands). The affected lymphocytes lose their infection-fighting properties, making one more vulnerable to infection. More...
04 Jan 2022
Illustration

Blood Test Combines AI and Machine Learning to Detect Cancer Before It Becomes Visible or Symptomatic

A simple blood test combines Artificial Intelligence (AI) and Machine Learning (ML) advances to identify cancer before it is visible or symptomatic. More...
28 Dec 2021
Image: Blood film from a patient with Monoclonal B-cell lymphocytosis. The circulating atypical lymphocytes are mature with a small rim of basophilic cytoplasm. Monoclonal population of B cells in the blood is less than 5 ×109/L (Photo courtesy of Elizabeth Courville, MD)

Tissue Counterpart to Monoclonal B-Cell Lymphocytosis Characterized

Monoclonal B-cell lymphocytosis (MBL) was initially proposed to recognize patients with a monotypic B-cell population identified by peripheral blood (PB) flow cytometry (FC) that did not meet numerical criteria for chronic lymphocytic leukemia (CLL). More...
27 Dec 2021
Image: Schematic graphics showing how variation in common laboratory test results caused by ambient temperature (Photo courtesy of Cell Press)

Seasonal Temperature Impacts Patients’ Laboratory Results

Every year, 13 billion laboratory tests are performed in the USA, nearly 800 million in the UK, and many more worldwide. Test results provide critical data on clinically important changes in patient physiology. More...
23 Dec 2021
Illustration

Qiagen and Denovo Biopharma to Develop Blood-Based CDx Test for Treatment of Diffuse Large B-Cell Lymphoma

QIAGEN N.V. (Venlo, Netherlands) and Denovo Biopharma LLC (San Diego, CA, USA) have entered into a collaboration to develop a blood-based companion diagnostic (CDx) test to identify patients expressing Denovo Genomic Marker 1 (DGM1TM) who are likely to respond to Denovo’s investigational cancer drug DB102TM for treatment of diffuse large B-cell lymphoma (DLBCL), one of the most common lymphoid cancers. More...
21 Dec 2021
Illustration

New Diagnostic Blood Test Could Reveal Early Stage Lung Cancer in Asymptomatic Patients

A diagnostic blood test may provide early detection of lung cancer in asymptomatic patients, according to a new study. More...
16 Dec 2021
Image: Histopathology of Allergic bronchopulmonary aspergillosis. Grocott\'s Methenamine Silver Stain  shows branching and helps to confirm that the black structures are indeed fungal hyphae (Photo courtesy of Doctorlib)

Pulmonary Eosinophilia Indicates Onset of Allergic Bronchopulmonary Aspergillosis

Allergic bronchopulmonary aspergillosis (ABPA) is a pulmonary disorder caused by type 2 immune responses to Aspergillus. This pathology usually develops after the onset of bronchial asthma (BA) or cystic fibrosis. Rates differ among countries, but appear to be increasing around the world with the increase of BA. More...
13 Dec 2021
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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