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Clinical Chemistry

Image: The AU5800 fully automated biochemical analyzer (Photo courtesy of Beckman-Coulter)

Urinary NAG-Creatine Ratio Predicts Advanced Diabetic Kidney Disease

Diabetes is the leading cause of chronic kidney disease and end-stage kidney disease worldwide and becomes one of the biggest healthcare challenges of the 21st century. Microvascular complications have been identified as the common and major diabetic complications. More...
03 Jan 2023
Image: The BÜHLMANN fCAL ELISA is a microtiter based assay kit for determination of calprotectin in fecal samples (Photo courtesy of Bühlmann Laboratories)

Impact of Preanalytical Factors on Calprotectin Concentration in Stool

In inflammatory bowel disease (IBD), fecal calprotectin measurement is increasingly important in selecting patients for diagnostic endoscopy, monitoring of disease activity, and evaluation of treatment response. More...
29 Dec 2022
Image: Histopathological characteristics of immune checkpoint inhibitor–associated myocarditis (Photo courtesy of The University of Texas MD Anderson Cancer Center)

Biomarkers Associated With Immune Checkpoint Inhibitor Myocarditis Revealed

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of various malignancies. The development and widespread use of ICIs have led to improved outcomes with a generally better tolerated side-effect profile compared with other therapies. More...
27 Dec 2022
Image: Blood Test for anti-Müllerian hormone (AMH) that relates differently to lipids/lipoproteins profile in women during midlife (Photo courtesy RMA of New York)

Anti-Müllerian Hormone Linked to Lipid Levels in Midlife Women

Throughout the period before, during and after menopause, also known as the menopause transition, midlife women are at a heightened risk for cardiovascular disease with changes in their lipid levels, such as a sharp increase in low-density lipoprotein cholesterol (LDL-C). More...
20 Dec 2022
Image: Low levels of ergothioneine in blood plasma may predict increased risk of cognitive impairment and dementia (Photo courtesy of NUS)

Simple Blood Test Can Detect Predictive Biomarker for Cognitive Impairment and Dementia

A new study has revealed that low levels of ergothioneine (ET) in blood plasma may predict an increased risk of cognitive impairment and dementia, suggesting possible therapeutic or early screening measures for cognitive impairment and dementia in the elderly. More...
20 Dec 2022
Image: The cobas 8000 modular analyzer series is a scalable module based serum work area (SWA) solution for a wide range of in vitro diagnostics testing of clinical chemistry & immunochemistry designed for high throughput laboratories (Photo courtesy of Roche Diagnostics)

CSF Glucose Unaltered in Patients With Dementia

A plethora of the pathological processes of many dementia disorders begin several years before the clinical expression of the diseases, and for that reason it is important to discover new biomarkers and methods to detect these processes at an early stage. More...
14 Dec 2022
Image: The multi-cancer early detection method measures cancer-indicating changes in so-called glycosaminoglycans (Photo courtesy of Chalmers)

Ground-Breaking New Method for Multi-Cancer Early Detection Is More Practical and Cheaper

Researchers have developed a new method for Multi-Cancer Early Detection (MCED) that is based on human metabolism. The results uncover new opportunities for cheaper and more effective cancer screening.  More...
08 Dec 2022
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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