Automated Microscope Alerts Diagnosticians to Possible Cell Anomalies

The robotic handling system will remove each slide one by one and scan the cells to see which ones are abnormal. The machine tells the technician which cells looked suspicious, and he can then spend a couple minutes checking only those.

Petros Tsipouras, professor of biology at the University of Athens (Greece) and Ikonisys chairman and CEO, said that the system could lead to a noninvasive alternative to amniocentesis or chorionic villus sampling to check fetuses for chromosomal abnormalities that could indicate Downs Syndrome.

The system could also look for cancer cells shed by a tumor and circulating in the bloodstream, even when the tumor is too small to image. Such a test could be a useful backup to the prostate specific antigen (PSA) tests given to men to look for prostate cancer and would cut down on unnecessary biopsies

The company has begun marketing the automated system, starting with a test for bladder cancer and another for abnormalities on amniocytes that would indicate birth defects. It plans to introduce another test, based on a third-party reagent, to look for signs of breast cancer.

Ikonisys has launched a clinical laboratory for its rare-cell-based tests. Under Food and Drug Administration (FDA; Silver Spring, MD, USA) “home brew” rules, the company can use its tests in-house before it receives FDA approval to sell to others.

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Ikonisys
University of Athens
Food and Drug Administration