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Molecular Diagnostics

Image: An innovative ELISA kit can identify diabetes patients at higher risk of developing lethal cardiovascular disease or renal failure (Photo courtesy of MyGenetx).

Haptoglobin Genotyping Test Enables Key Diabetes Treatment

A breakthrough ELISA kit, based on the Haptoglobin 2-2 (Hp 2-2) protein marker, can identify diabetes patients at higher risk of developing lethal cardiovascular disease or renal failure, thereby enabling them to take Vitamin E, a nutritional supplement shown to be of great benefit to them but posing harm to the remaining non-HP 2-2 diabetic population. An application for the CE mark for the test is currently in progress, with FDA certification planned for the US market. More...
29 May 2017
Image: Scientists have identified a genetic mutation that contributes to sight loss in children (Photo courtesy of the University of Edinburgh).

Recurrent Mutation Linked to Childhood Blindness

Researchers have identified a genetic mutation that contributes to the sight loss that occurs in children with ocular coloboma, a developmental defect that causes part of the eye to be missing at birth. The findings shed light on its causes and help explain how genes contribute to development of the eye. More...
29 May 2017
Image: Drops of blood on filter paper, easy to store for future diagnostics (Photo courtesy of Jan Björkeste, Uppsala University).

Blood Sample Storage Evaluated for PEA Analysis

A team of Swedish researchers evaluated and optimized conditions for storing samples of dried blood for current and future proximity extension assay (PEA) analysis. More...
29 May 2017
Image: Research suggests identifying small molecules in saliva will help identify those at risk of developing Alzheimer\'s disease (Photo courtesy of Getty Images).

Metabolic Approach Helps Determine Risk of AD

Measurement of metabolites in saliva samples has been suggested as a noninvasive approach for determining risk of developing Alzheimer's disease. More...
29 May 2017
Image: According to a new study, a gene mutation may accelerate the loss of memory and thinking skills in people who are at risk for Alzheimer’s disease (Photo courtesy of iStock).

Alzheimer’s Disease Progression Predicted by Gene Mutation

Alzheimer's disease is the most common form of dementia in older adults. It is a degenerative condition, characterized by a steady loss of memory and a reduced ability to carry out daily activities. Today, an estimated five million people in the USA are living with the disease. More...
25 May 2017
Image: E. coli (shown here growing on an agar plate) is three-fold more common in advanced NAFLD patients than early stage patients, according to a recent study (Photo courtesy of the University of California San Diego School of Medicine / J. Craig Venter Institute).

Pathogens Help Diagnose Fatty Liver Disease

Nonalcoholic fatty liver disease is a condition characterized by a buildup of fat in the liver and the condition is often not detected until it is well advanced, and a definitive diagnosis requires an invasive biopsy of the liver. More...
25 May 2017
Image: Endometriosis in the peritoneal tissue (left) forming a scar. Under microscopy, it is composed of glands and surrounding stroma with chronic inflammation and fibrosis (Photo courtesy of Ie-Ming Shih).

Gene Sequencing Reveals Mutations in Endometriosis

Endometriosis occurs when tissue lining the uterus forms and grows outside of the organ, most often into the abdomen. The disease occurs in up to 10% of women before menopause and half of those with abdominal pain and infertility problems. More...
24 May 2017

Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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