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Immunology

Image: The Simoa HD-1 Analyzer is a fully automated instrument for running immunoassays (Photo courtesy of Quanterix).

Urinary Biomarkers for Tuberculosis Explored

The gold standard for tuberculosis (TB) diagnosis is the isolation in culture of Mycobacterium tuberculosis in biological samples. However, culture is time consuming and does not accomplish the need of quickly and properly starting treatment, it is not always feasible in extra-pulmonary TB and it is difficult to carry out in resource-limited settings. More...
25 Dec 2018
Image: The Lumipulse G 25-OH Vitamin D is an immunoreaction cartridge for in vitro diagnostic for the quantitative determination of 25-hydroxyvitamin D (25(OH)D) in human serum or plasma to be used in the assessment of Vitamin D sufficiency (Photo courtesy of Fujirebio).

Vitamin D Measured in Patients with Diabetic Foot

Peripheral artery disease (PAD) is the underlying predisposing factor in the etiology of the majority of diabetic feet. Vitamin D plays a role in calcium and bone metabolism and it is known to be an important immune modulator agent. More...
19 Dec 2018
Image: Patients with inflammatory bowel disease who have an elevated PSA, may be at risk for prostate cancer (Photo courtesy of Harvard University).

Inflammatory Bowel Disease Linked to Prostate Cancer

About one million men have inflammatory bowel disease in the USA, a common chronic condition that includes Crohn's disease and ulcerative colitis. Epidemiologic studies have noted an association between chronic inflammation and prostate cancer. More...
18 Dec 2018
Image: A section from the hippocampus of an Alzheimer’s disease patient stained with a tau antibody (TNT1). Note the classical triad of tau pathologies in AD, 1) neurofibrillary tangles (arrowheads), 2) neuropil threads (arrows), and 3) a neuritic plaque (asterisk) (Photo courtesy of Michigan State University).

Tau Blood Test Developed for Alzheimer's Disease

Presently, the only way to definitively diagnose Alzheimer's disease in life is through brain scans and tests of cerebrospinal fluid that must be collected via lumbar puncture. Though cumbersome and expensive, such tests provide the most accurate diagnoses for patients. More...
17 Dec 2018
Image: A histopathology of Strongyloides stercoralis in the duodenum (Photo courtesy of Dr. Raul S. Gonzalez, MD).

Strongyloidiasis Antibodies Found in Transplant Donors

Strongyloidiasis is a neglected tropical disease caused by a parasite, which is endemic in most parts of the world. It can cause a life-threatening disease among immunosuppressed individuals and can be transmitted from solid organ transplant (SOT) donors to recipients. More...
10 Dec 2018
Image: The BC-5390CRP blood cell analyzer (Photo courtesy of Mindray).

Potential Biomarkers Found for Acute Aortic Dissection

An aortic dissection is a serious condition in which the inner layer of the aorta, the large blood vessel branching off the heart, tears. Blood surges through the tear, causing the inner and middle layers of the aorta to separate (dissect). More...
10 Dec 2018
Image: The ARCHITECT B.R.A.H.M.S PCT assay, which is a two-step immunoassay using chemiluminescent microparticle immunoassay (CMIA) technology (Photo courtesy of Abbott Laboratories).

Commercial Fully Automated Procalcitonin Immunoassay Compared

Procalcitonin (PCT), a 13-kDa peptide precursor of calcitonin, has gained widespread acceptance as an early and specific biomarker for the presence of systemic bacterial infection. In particular, PCT monitoring has demonstrated value in guiding antibiotic use for bacterial infections. More...
04 Dec 2018
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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