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Immunology

Image: Schematic representation of the remote electrochemiluminescence (ECL) mechanism (Photo courtesy of University of Bologna).

Increasingly Efficient Serological Tests Developed with Electrochemiluminescence

Diagnostic markers, or biomarkers, are biomolecules (e.g., enzymes, proteins, peptides, and hormones) that can be measured accurately and reproducibly and can precisely predict relevant clinical outcomes or diseases in various populations. More...
17 Jun 2020
Image: Myeloid-derived suppressor cells in the tumor microenvironment have been observed in a variety of solid tumors (Photo courtesy of BMS Immuno-Oncology).

Tumor Mutation and Immune Microenvironment Revealed in Colorectal Cancer

Most colorectal cancers are due to old age and lifestyle factors, with only a small number of cases due to underlying genetic disorders. Other risk factors include diet, obesity, smoking, and lack of physical activity. Dietary factors that increase the risk include red meat, processed meat, and alcohol. More...
10 Jun 2020
Image: Four Plasmodium vivax parasites have invaded human hepatocytes. Three of the parasites are developing while one parasite, on the lower left, is a dormant hypnozoite, which remains small until its reactivation (Photo courtesy of Nil Gural).

Serological Exposure Markers Developed for Vivax Malaria

Plasmodium vivax is the most widespread malaria parasite worldwide, with up to two billion people at risk of infection. As well as causing illness and death in its 'active' stage of infection, the parasite can hide as hypnozoites, a dormant stage, in the liver, and is a significant cause of 'relapsing' malaria. More...
10 Jun 2020
Image: The QSight Triple Quad 400 Series Liquid Chromatography Mass Spectrometry (Photo courtesy of PerkinElmer).

Endogenous Testosterone Levels Associated with Risk of Diabetes

High plasma levels of endogenous total and circulating free testosterone are associated with a two- to sevenfold increased risk for developing type 2 diabetes among young, healthy women without comorbidities. More...
02 Jun 2020
Image: The Cytokine Magnetic 30-Plex Panel is specifically designed for quantifying human cytokines, chemokines and growth factors in serum, plasma, and tissue culture supernatant (Photo courtesy of Invitrogen).

Cytokine Signatures of Tertian Malaria Infection Profiled During Pregnancy

Malaria caused by Plasmodium vivax is a neglected tropical disease, especially during pregnancy, of worldwide distribution. P. vivax is a protozoal parasite and a human pathogen. This parasite is the most frequent and widely distributed cause of recurring malaria. More...
27 May 2020
Image: Schematic diagram of ultrabright fluorescence readout of an inkjet-printed immunoassay using plasmonic nanogap cavities (Photo courtesy of Duke University).

Silver Nanocubes Make Point-of-Care Diagnostics Easier to Read

Plasmonics is a scientific field that traps energy in a feedback loop called a plasmon onto the surface of silver nanocubes. When fluorescent molecules are sandwiched between one of these nanocubes and a metal surface, the interaction between their electromagnetic fields causes the molecules to emit light much more vigorously. More...
27 May 2020
Image: CTL- Immunospot Analyzers come in a wide range of models, each of which is designed to make assay analysis faster, easier, and more accurate than ever before (Photo courtesy of Cellular Technology Limited).

Initial Immune Response After Dengue Virus Infection Identified

Dengue virus (DENV) is a member of the clinically-relevant Flavivirus genus together with Zika virus, yellow fever virus and others. With four distinct serotypes, DENV is thought to infect between 280 and 550 million people worldwide every year. More...
19 May 2020
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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