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Immunology

Image: Electron micrograph of Coronaviruses which take their name from their crown-like halo (Photo courtesy of EYE OF SCIENCE/SPL).

Global Coronavirus Crisis: Researchers, Industry Mobilize to Offer Remedies (Updated)

In light of the worsening global Coronavirus health crisis, the In-Vitro Diagnostics sector around the world is racing to develop a definitive test for the COVID-19 virus. Several such assays are currently in the pipeline, and some are to be marketable within weeks. More...
09 Mar 2020
Image: PAX5/CD103 dual immunohistochemistry (IHC) staining showing no definite dual-positive cells, PAX5 stain showing brown nuclear staining in nonneoplastic B cells and CD103 showing membranous and cytoplasmic staining in a subset of T cells (Photo courtesy of US National Institute of Cancer).

Dual Immunohistochemistry Bone Marrow Staining Detects Hairy Cell Leukemia

 Hairy cell leukemia (HCL) is a B-cell lymphoproliferative disorder characterized by distinct immunophenotype (positive for CD19, CD20, PAX5, CD22, CD11c, CD25, CD103, CD123, and CD200). Immunophenotypic analysis by flow cytometry (FC) is considered the gold standard for diagnosis of HCL. More...
03 Mar 2020
Image: MACS Technology is a fast and gentle method for the isolation of viable and functionally active cells by magnetic labeling (Photo courtesy of University of Konstanz).

Fetal Cell-Based NIPT Demonstrated by Droplet Digital PCR

 Noninvasive testing techniques are often used for fetal diagnosis of genetic abnormalities, but are limited by certain characteristics, including non-informative results. Thus, novel methods of noninvasive definitive diagnosis of fetal genetic abnormalities are needed. More...
27 Feb 2020
Image: This photomicrograph depicts T cells interacting with each other. Cell surfaces are labeled in red, cell nuclei in blue, and receptors mediating communication in green (Photograph courtesy of Immunity).

T Cells Function as A Team to Fight Infection

 When faced with an infection, T cells normally follow a remarkably reproducible response pattern of expansion, contraction, and memory formation. Population-intrinsic and -extrinsic regulation of T cells occur, but are not mutually exclusive. More...
26 Feb 2020
Image: The V-PLEX Proinflammatory Panel 1 Human Kit measures 10 cytokines that are important in inflammation response and immune system regulation as well as numerous other biological processes (Photo courtesy of Meso Scale Discovery).

Novel Blood Tests Predict Progression of Parkinson's Disease

 It is well established that the cumulative incidence of dementia associated with Parkinson’s disease (PD) is approaching 80% and individuals with PD are five to six times more likely to develop cognitive impairment than age-matched controls. More...
25 Feb 2020
Image: The DENV Detect IgM Capture ELISA is for the qualitative detection of IgM antibodies to DENV recombinant antigens in serum for the presumptive clinical laboratory diagnosis of Dengue virus infection (Photo courtesy of InBios International).

Anti-Dengue Virus IgM Detected in Urine

 Dengue viruses (DENV) are transmitted to humans by infected mosquitoes and the disease, known as dengue, occurs throughout the tropics and subtropics. Dengue diagnostic tests rely on a blood sample taken within two weeks of illness onset. More...
20 Feb 2020
Image: The FUJI DRI-CHEM IMMUNO AG1 analyzer (Photo courtesy of FUJI FILM).

Rapid Antigenic Diagnostic Test Validated for Ebola Virus Disease

 Hemorrhagic fever outbreaks are difficult to diagnose and control in part because of a lack of low-cost and easily accessible diagnostic structures in countries where etiologic agents are present. Initial clinical symptoms are common and shared with other endemic diseases such as malaria or typhoid fever. More...
13 Feb 2020
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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