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Immunology

Image: Elevated levels of two inflammatory proteins, IL-12p70 and IFN-γ, were associated with slower cognitive decline in older adults (Photo courtesy of Scientific Animations Inc)

Two Inflammatory Proteins Linked with Slower Cognitive Decline

Previous meta-analyses of case-control and prospective cohort studies showed that cytokines and inflammatory markers, such as interleukin-6 (IL-6), C-reactive protein (CRP), and others are elevated in Alzheimer's dementia cases and predicted incident of all-cause dementia. More...
08 Jul 2021
Image: Enzyme-linked immunosorbent assay (ELISA) kit for Fatty acid-binding proteins 4 (FABP4) (Photo courtesy of Biovendor R&D)

FABP4 Concentrations Quantified in Proliferative Diabetic Retinopathy

Proliferative diabetic retinopathy (PDR), a progressive and serious stage of diabetic retinopathy (DR) due to retinal ischemia, is characterized by neovascularization (NV), vitreous hemorrhaging (VH) and tractional retinal detachment (TRD), all of which are major causes of blindness in patients with diabetes mellitus (DM). More...
07 Jul 2021
Image: The IDS-iSYS Multi-Discipline Automated System Analyzer (Photo courtesy of Immunodiagnostic Systems)

Two Immunoassays Compared for Determination of Serum Vitamin D

Vitamin D is a fat-soluble steroid prohormone that is generated mainly in the skin by photochemical conversion of 7-dehydrocholesterol. 25-hydroxyvitamin D (25(OH)D) is its main storage form and is present in blood at very high concentration with respect to the active form 1,25-dihydroxyvitamin D. More...
06 Jul 2021
Image: The Luminex200 Instrument System sets the standard for multiplexing, providing the ability to perform up to 100 different tests in a single reaction volume on a flow cytometry-based platform (Photo courts of Luminex Corporation)

Biological Markers Associated with Severe Dengue Identified

Dengue is the most common mosquito-borne viral disease to affect humans globally. In 2019, the World Health Organization identified dengue as one of the top 10 threats to global health, with transmission occurring in 129 countries and an estimated 3.9 billion people being at risk. More...
06 Jul 2021
Image: Anti-Ganglioside Antibodies Analyzed in Celiac Disease (Photo courtesy of Blood Tests London)

Anti-Ganglioside Antibodies Analyzed in Celiac Disease

Celiac disease, sometimes called celiac sprue or gluten-sensitive enteropathy, is an immune reaction to eating gluten, a protein found in wheat, barley and rye. Coeliac disease can cause a range of symptoms, including diarrhea, abdominal pain and bloating. More...
29 Jun 2021
Image: Enzyme-linked immunosorbent assay for the determination of anti-drug antibodies (Photo courtesy of Matriks Biotek)

Biomarker Predicts Crohn's Disease Relapse in Children

Crohn's disease is a type of inflammatory bowel disease (IBD). It causes inflammation of the digestive tract, which can lead to abdominal pain, severe diarrhea, fatigue, weight loss and malnutrition. Other complications outside the gastrointestinal tract may include anemia, skin rashes, arthritis, inflammation of the eye, and lethargy. More...
22 Jun 2021
Image: The Leptin enzyme-linked immunosorbent assay is for the quantitative determination of leptin in human serum (Photo courtesy of the American Laboratory Products Company)

Serum Leptin Concentration Predict Cardiovascular Outcomes in Hemodialysis Patients

Leptin, a 16-kDa protein product mainly secreted by adipocytes, has been known to increase energy expenditure, suppress appetite, and leads to weight loss. Hyperleptinemia was common in maintenance hemodialysis (MHD) patients, and it was likely to be one of the causes of anorexia and malnutrition. More...
21 Jun 2021
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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