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Hematology

Image: Bone marrow aspirate smear from a patient with myelodysplastic syndromes, unclassifiable (MDS-U) (pancytopenia and -7 cytogenetic abnormality). Occasional late mitotic figures in erythroid elements are present, but no significant erythroid or myeloid dysplasia exists (Photo courtesy of Dr. Robert P. Hasserjian, MD).

Disease Progression Apprised by Post-Treatment Mutation Sequencing

Allogeneic hematopoietic stem-cell transplantation is the only curative treatment for patients with myelodysplastic syndrome (MDS). The molecular predictors of disease progression after transplantation are unclear. More...
26 Sep 2018
Image: A blood film from a patient with acute myeloid leukemia (Photo courtesy of the University of Toronto).

DNA Test Predicts Risk of Leukemia Relapse

Acute myeloid leukemia (AML) is the most common type of leukemia in adults, comprising about one quarter of all cases. The disease stems from an overproduction of immature blood cells in the bone marrow, which over time outgrow normal blood cells. It's a type of cancer, which starts suddenly and progresses quickly, requiring urgent treatment. More...
25 Sep 2018
Image: The LSM 780 inverted laser scanning confocal microscope (Photo courtesy of Zeiss).

Biomarker Identified for Novel Asthma Treatment

Asthma is a widespread chronic airway disease characterized by airway obstruction, inflammation, and hyperresponsiveness. Symptoms such as bronchoconstriction and cough range from mild intermittent to severe persistent. More...
17 Sep 2018
Image: A blood film from a patient with Chronic Lymphocytic Leukemia (CLL); a large lymphocyte (arrow) has a notched nucleus and demonstrates the variable appearance of some of the lymphocytes in CLL (Photo courtesy of Peter Maslak).

New mRNA Cancer Drivers Revealed in Chronic Lymphocytic Leukemia

New evidence has emerged showing that the inactivation or alteration of cancer suppressor genes can take place even if DNA itself remains unaltered. A known molecular mechanism for cancer development and spread is the inactivation of tumor suppressor genes, which encode various tools the body uses to keep its cells from turning cancerous. More...
11 Sep 2018
Image: Bone marrow aspirate from a patient with diffuse large B cell lymphoma (Photo courtesy of Peter Maslak).

Blood Test Predicts Lymphoma Therapy Success

A blood test can predict which patients with a type of cancer called diffuse large B cell lymphoma are likely to respond positively to initial therapy and which are likely to need more aggressive treatment. More...
04 Sep 2018
Image: Multiple myeloma, a cancer of the blood plasma (Photo courtesy of Medical News Today).

Multi-Omics Approach Guides Relapsed Multiple Myeloma Treatment

Many patients with relapsed multiple myeloma are not often matched with correct treatment options in a timely or personalized manner, and most patients have a median survival rate of six years. With standard diagnosis and treatment, relapses are usually inevitable and fatal for most patients. More...
30 Aug 2018
Image: The STA COMPACT MAX 2 is a fully automated benchtop analyzer (Photo courtesy of Diagnostica Stago).

Coagulation Tests Affected by Sodium Citrate Concentration

Despite a high degree of standardization, coagulation tests largely depend on preanalytic factors. Apart from artifacts acquired during blood drawing and transportation, the in vitro anticoagulant used has a potential impact on the coagulation test result. More...
27 Aug 2018
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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