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Hematology

Image: The small plastic chip about the size of a credit card that can deliver the same diagnostic information as a bone marrow biopsy but using a simple blood draw instead (Photo courtesy of the University of Kansas).

Chip-Based Blood Test Developed for Multiple Myeloma

The diagnosis of multiple myeloma, a cancer affecting plasma cells, traditionally forces patients to suffer through a painful bone biopsy. Doctors insert a bone-biopsy needle through an incision to get a bone marrow sample or make a larger incision and remove a section of bone via surgery. More...
03 May 2018
Image: The 3D printed devices can capture microscopic images, when attached to a smartphone camera lens (Photo courtesy of Ozcan Research Group/UCLA).

Smartphone Microscopes Transformed into Lab Devices

Mobile phones have facilitated the creation of field-portable, cost-effective imaging and sensing technologies that approach laboratory-grade instrument performance. However, the optical imaging interfaces of mobile phones are not designed for microscopy and produce distortions in imaging microscopic specimens. More...
25 Apr 2018
Image: The Navios clinical flow cytometer (Photo courtesy of Beckman Coulter).

Flow Cytometry Technique Assessed for Signaling Pathways

Platelet aggregation is a key parameter in arterial thrombosis, leading to myocardial infarction or ischemic stroke. Platelets have several receptors sensitive to different stimuli and drugs that modulate aggregation with potential critical clinico-pathological significance. More...
24 Apr 2018
Image: The Architect i2000SR immunoassay analyzer (Photo courtesy of Abbott Diagnostics).

Chronic Fatigue Syndrome Linked to Thyroid Levels

Chronic fatigue syndrome (CFS) is a common disease marked by lengthy spells of weakness, fatigue and depression. Its diagnosis is predominantly based on symptoms and on ruling out any underlying medical condition, rather than on laboratory tests and physical examination. More...
04 Apr 2018
Image: A histopathology of a deep vein inflammatory infiltrate with wall dissociated by edema, observed in a skin lesion of a leprosy patient suffering an erythema nodosum leprosum episode (Photo courtesy of Oswaldo Cruz Institute).

Unusual Blood Clots Characterized in Leprosy Patients

Leprosy is a chronic infection by Mycobacterium leprae and causes body-wide symptoms, deformities, and disability. It remains a public health problem worldwide, despite the existence of antibiotic combinations that can cure it. More...
03 Apr 2018
Image: The BD FACSCanto II flow cytometer analyzer (Photo courtesy of BD Biosciences).

Flow Cytometry Detects Myelodysplasia in Peripheral Blood

Myelodysplastic Syndromes (MDS) are a group of myeloid neoplasms characterized by inefficient hematopoiesis, peripheral blood (PB) cytopenias and high risk of leukemic progression. More...
27 Mar 2018
Image: Chromosomes with telomeres at their tips, in green. The intensity of the green signal is one indicator of telomere length, which is a measure of cellular “aging” and determines how many times a cell can divide (Photo courtesy of Professor George Daley, MD, PhD).

Telomere Length Test Influences Treatment Decisions

Telomeres protect the ends of DNA and they normally shorten with aging. They are made up of repetitive sequences of DNA, and normal telomeres have enough length to withstand the erosion that occurs over the normal lifespan of a cell. More...
13 Mar 2018
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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