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Molecular Diagnostics

Image: A new blood test has been developed for detecting recent exposure to `relapsing` or vivax malaria (Photo courtesy of Mayeta Clark, Walter and Eliza Hall Institute, Australia)

New Blood Test Can Determine When an Individual Was Exposed to a Pathogenic Microorganism

An international research team has developed a diagnostic blood test – initially for the recurring form of vivax malaria – that can determine when an individual was exposed to a pathogenic microorganism, including the coronavirus that causes COVID-19. More...
19 May 2020
Image: Schematic diagram of Molecular Characterization Identifying Distinct Molecular Hallmarks of Renal Medullary Carcinoma (Photo courtesy of University of Texas MD Anderson Cancer Center).

Rare Kidney Cancer Marked by Molecular Features

Renal medullary carcinoma is a rare cancer of the kidney that predominantly afflicts young people of African descent who carry the sickle cell trait, sickle cell disease, or other sickle hemoglobinopathies that can cause sickling of the red blood cells. More...
19 May 2020
Image: Structure of the angiotensin-converting enzyme 2 (ACE2) protein (Photo courtesy of Wikimedia Commons)

Higher Concentrations of COVID-19 Receptor Protein Found in Men’s Plasma

Results of a large-scale study revealed that plasma concentrations of angiotensin-converting enzyme 2 (ACE2) were higher in men than in women, but use of neither an ACE inhibitor nor an angiotensin receptor blocker (ARB) was associated with higher plasma ACE2 concentrations. More...
18 May 2020
Image: Schematic diagram of circulating tumor DNA (ctDNA) which is found in serum and plasma fractions from blood. The mechanism of ctDNA release is unknown, though apoptosis, necrosis, and active secretion from tumor cells have been hypothesized. Once ctDNA is isolated, it can be sequenced for mutational analysis (Photo courtesy of Rachel June Wong).

Blood Test Shows Promise for Predicting Cancer

Early detection of most cancers is an elusive and daunting task; nevertheless, it has remained a top priority for the cancer research community. Detecting cancer early has manifold advantages: it can increase a patient’s chances of successful treatment, prolong their survival, and substantially improve their quality of life. More...
14 May 2020
Image: High magnification micrograph of diffuse proliferative lupus nephritis (Photo courtesy of Wikimedia Commons).

Knowing the Ethnic Specificity of Urinary Biomarker Proteins Could Refine Diagnosis of Lupus Nephritis

A study of biomarkers in the urine of African-Americans, Caucasian, and Asian patients suffering from lupus nephritis identified distinct patterns of proteins associated with each specific ethnicity, which may be useful in diagnosing the disorder. More...
13 May 2020
Image: Scanning electron microscope image (500x magnification) of pollen grains from a variety of common plants (Photo courtesy of Dartmouth Electron Microscope Facility, Dartmouth College (via Wikimedia Commons)

Biomarker Panel Predicts Severity of Pollen Allergy Symptoms

A team of German researchers has identified a panel of biomarkers that predicts the severity of allergic symptoms even before the start of the pollen season. More...
12 May 2020
Image: Multicancer Blood Test Aids Screen for Cancer Guide Intervention (Photo courtesy of fotoquique/Depositphotos).

Multicancer Blood Test Aids Screen for Cancer Guide Intervention

As minimally invasive screening tests, liquid biopsies could help reduce cancer-specific morbidity and mortality through earlier detection. However, there is debate on how to effectively screen large populations for cancer, including individuals who do not have symptoms or history of the disease. More...
12 May 2020
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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