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Clinical Chemistry

Image: Troponin T binds to tropomyosin and helps position it on actin, and with the rest of the troponin complex modulates contraction of striated muscle. In patients with stable coronary artery disease, troponin T concentrations have been found to be significantly associated with the incidence of cardiovascular death and heart failure (Photo courtesy of Wikimedia Commons).

Elevated Blood Sugar a Cardiovascular Disease Risk Not Linked to Cholesterol Levels

Individuals with prediabetes and diabetes are at high risk for cardiovascular events such as myocardial infarction that can be predicted by elevated levels of troponin T.  More...
21 Sep 2014
Image: An acoustically powered pumping device with 250 micron long oscillating structures driven by a piezoelectric transducer mounted on a glass slide shown next to US copper penny (Photo courtesy of Po-Hsun Huang and Tony Jun Huang).

Micropump Developed for Lab-On-A-Chip Disease Diagnosis

A reliable, inexpensive, programmable pump is a crucial feature for lab-on-a-chip devices that could make the diagnosis of many global life-threatening diseases easy and affordable.  More...
18 Sep 2014
DIASOURCE (A Biovendor Company)
Image: Researchers have demonstrated potential for a new, noninvasive method to screen for prostate cancer using a detection system that combines surface-enhanced Raman scattering (SERS) with support vector machine (SVM) techniques (Photo courtesy of Prof. S. Li and Guangdong Medical College).

Novel Method Developed for More Effective Noninvasive Prostate Cancer Screening

Comparing healthy volunteers and prostate cancer patients, researchers have successfully shown that their new method, which builds on the use of SERS spectroscopy of silver nanoparticles mixed with blood samples, could reveal cases of cancer.  More...
16 Sep 2014
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Specific Blood Test Diagnoses Early Onset Kidney Failure

A new and dedicated reagent for the measurement of cystatin C on a portable centrifuge-method clinical chemistry analyzer has been released.  More...
16 Sep 2014
Image: Histopathology of a heart demonstrating fibrosis and myocardial disarray in hypertrophic cardiomyopathy from a case of sudden cardiac arrest (Photo courtesy of Candace H Schoppe, MD).

Sex Hormone Levels Linked to Sudden Cardiac Arrest Risk

The measurement of the levels of sex hormones in patients' blood may identify patients likely to suffer a sudden cardiac arrest, a heart rhythm disorder that can be fatal in most patients.  More...
15 Sep 2014
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Novel Method Identifies Fat Malabsorption

A novel clinical test known as the Serum Retinyl Palmitate Test has been assessed and validated for the diagnosis of fat malabsorption, and compared to the fecal fat test.  More...
10 Sep 2014
Image: The Zinc Transporter 8 Autoantibody (ZnT8Ab) enzyme-linked immunosorbent assay (ELISA) kit (Photo courtesy of KRONUS).

Autoantibody Test Helps Diagnose Type 1 Diabetes

The first zinc transporter 8 autoantibody test has been approved for marketing and the test can help determine if a person has diabetes mellitus type 1 and not another type of diabetes.   More...
09 Sep 2014
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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