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Clinical Chemistry

High-Sensitivity Version of Common Blood Test May Predict Early Onset of Hypertension

A study analyzing blood samples from over 5,000 people suggests that a more sensitive version of the standard blood test for cardiac troponin T—long used to verify heart muscle damage from heart attacks—could help identify people on the verge of developing hypertension well before it can be detected with a blood pressure machine.  More...
02 Sep 2015
Image: The Agilent 1200 high-performance liquid chromatography system (Photo courtesy of Marine Biophysics Laboratory).

Biomarkers Identified for Early Lung Cancer Diagnosis

Lung cancer can be diagnosed early with regular low-dose computed tomography scans of people at risk, but these tests are very expensive, and also involve exposing patients to X-ray radiation.  More...
01 Sep 2015
DIASOURCE (A Biovendor Company)
Image: Photomicrograph demonstrating typical multiple myeloma histology, with monoclonal proliferation of plasma cells (Photo courtesy of Ohio State University College of Medicine).

Near Real-Time Osteoporosis and Bone Cancer Test Developed

 A new test which measures changes in calcium isotope ratios offers the possibility of near real time monitoring of bone diseases, such as osteoporosis and multiple myeloma. More...
30 Aug 2015
Image: Schematic representation of the protein biomarkers used in the Cardiac Protein Unstable Lesion Signature (PLUs) test (Photo courtesy of GD Biosciences).

Blood Test Detects Silent Cardiac Disease

A blood test has been developed that detects silent cardiac disease and assesses a person’s risk of suffering from a future cardiac event.   More...
26 Aug 2015
Image: The Capnogard 1265 capnometer (Photo courtesy Novametrix Medical Systems Inc.).

Breath Test Indicates Biomarker for Early-Stage Liver Disease

Patients with liver disease do not often present with symptoms until the disease is advanced and even then diagnosis is difficult and the symptoms and signs are often general and can be mistaken for other pathologies.  More...
24 Aug 2015
Image: The Single Molecule Array (Simoa) HD-1 Analyzer (Photo courtesy of Quanterix Corporation).

Sensitive Analyzer Detects Blood Biomarker for Traumatic Brain Injury

Traumatic brain injury is recognized as the signature injury in military personnel deployed for combat operations, and combat injuries and injuries in non-deployed settings have resulted in more than 300,000 TBI cases, with many experiencing multiple TBIs.  More...
18 Aug 2015
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Serum Mimecan Associated with Arterial Stiffness in Hypertensive Patients

Mimecan plays an important role in endothelial and vascular smooth muscle cell integrity and may be involved the pathology of arterial stiffness; however, the role of mimecan in arterial stiffness in patients with hypertension is not well defined.    More...
18 Aug 2015
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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