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Clinical Chemistry

Image: The COBAS c501 clinical chemistry analyzer (Photo courtesy of Roche Diagnostics).

Serum Magnesium Levels Linked to Dementia Risk

People with both high and low levels of magnesium in their blood may have a greater risk of developing dementia. Scientists have set out to find out if serum magnesium levels are associated with the risk of all-cause dementia and Alzheimer disease. More...
05 Oct 2017
Image: The UF-5000 fully automated urine analyzer (Photo courtesy of Sysmex Europe).

New Urine Analyzer Evaluated for Performance

Urinalysis is one of the most commonly requested laboratory tests, the third after the biochemical profile and the blood cell count, and it is very useful to screen for diseases of the kidney and urinary tract. More...
02 Oct 2017
Image: The qualitative point-of-care test CareStart G6PD RDT is a visual screening test that identifies G6PD deficient patients using whole blood sample. Panel A, no color change for sample with deficient G6PD enzymatic activity; Panel B, distinct purple color for sample with normal G6PD enzymatic activity (Photo courtesy of Access Bio).

Field Evaluation of Quantitative G6PD Diagnostics Reviewed

Glucose-6-phosphate dehydrogenase deficiency (G6PDd) is the most common enzymopathy with at least 400 million individuals affected worldwide. More than 185 clinically relevant variants of G6PDd have been reported with a spectrum of associated enzyme deficiencies. More...
27 Sep 2017
Image: Gas chromatography-tandem mass spectrometry GCMS TQ-8030 GC-MS/MS (Photo courtesy of Shimadzu).

Biomarkers Prove Role of Food for Diabetics

Diet is frequently associated with both the development and prevention of type 2 diabetes (T2D), but there is a lack of objective tools for assessing the relation between diet and T2D. More...
27 Sep 2017
Image: An illustration of the ZnT8 protein imbedded in a fatty membrane and attached to the P-Gold Assay (Photo courtesy of Dr. Dax Fu).

Pancreatic Proteins Increase Sensitivity of Type 1 Diabetes Tests

There are approximately 29.1 million people living with diabetes and about 18,000 children in the USA are diagnosed with type 1 diabetes, with diagnoses peaking around the age of 14. The disease is controllable with insulin injections, pumps and constant blood sugar testing. More...
27 Sep 2017
Image: The Affymetrix Genome-Wide Human SNP Array 6.0 features 1.8 million genetic markers including more than 906,600 single nucleotide polymorphisms (SNPs) and more than 946,000 probes for the detection of copy number variation (Photo courtesy of Thermo Fisher Scientific).

Type 2 Diabetes Misdiagnosed in African Americans

Glycated hemoglobin (HbA1c) is used to diagnose type 2 diabetes (T2D) and assess glycemic control in patients with diabetes. Previous genome-wide association studies (GWAS) have identified 18 HbA1c-associated genetic variants. More...
27 Sep 2017
Image: The infinite F50 absorbance reader (Photo courtesy of Tecan).

Low-Volume Aldosterone Immunoassay Validated for Small Samples

Heart failure is a severe cardiovascular disease in adults and children and is characterized by structural or functional abnormalities of the heart. Heart failure leads to an inappropriate blood circulation and subsequently to an undersupply of metabolizing tissues with oxygen and nutrients. More...
26 Sep 2017
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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