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Clinical Chemistry

Amine Biomarkers Identify Risk of Alzheimer's Disease

The identification of novel biomarkers associated with Alzheimer's disease (AD) could provide key biological insights and permit targeted preclinical prevention. Circulating metabolites associated with incident dementia and AD has been investigated using metabolomics. More...
30 Jun 2017

Blood Test Detects Heart Attack Risk in Lupus Patients

Systemic Lupus Erythematosus (Lupus) is a genetically complex chronic relapsing immune mediated rheumatic disease characterized by inflammation that may affect different tissues, including the skin, joint linings, lungs, kidneys and other organs. More...
29 Jun 2017
Image: A patient undergoing a breath test for chronic obstructive pulmonary disease and other lung diseases (Photo courtesy of Professor Malcolm Kohler, MD).

Exhaled Breath Test Discriminates COPD

Chronic obstructive pulmonary disease (COPD) is a type of obstructive lung disease characterized by long-term poor airflow. The main symptoms include shortness of breath and cough with sputum production. COPD is a progressive disease, meaning it typically worsens over time. More...
28 Jun 2017
Image: The ABI-Prism 3500 genetic analyzer (Photo courtesy of Applied Biosystems).

Lab Evidence Confirms Outbreak of Haff Disease

Haff disease is a syndrome of unexplained rhabdomyolysis following consumption of certain types of fish, and it is caused by an unidentified toxin. Rhabdomyolysis is a clinical syndrome caused by injury to skeletal muscle that results in release of muscle cell contents into the circulation. More...
28 Jun 2017
Image: The Gentian NGAL Immunoassay is a new particle-enhanced turbidimetric immunoassay (PETIA) for in vitro diagnostic testing of neutrophil gelatinase-associated lipocalin (NGAL) in human urine and plasma samples (Photo courtesy of Gentian).

Enhanced Immunoassay Validated for NGAL

The ectopic expression of Neutrophil Gelatinase-Associated Lipocalin (NGAL) has been reported in patients with various malignancies such as kidney, colorectal, gastric, pancreatobiliary, hepatic, breast, gynecological and hematologic cancers. More...
28 Jun 2017

Cholesterol Test May Help Assess Heart Disease Risk

Researchers have developed a first-of-its-kind rapid assay for measuring effectiveness of a patient’s high-density lipoprotein cholesterol (HDL-C) in cleaning up arterial cholesterol. This HDL-C function test could improve risk assessment and diagnosis, and help provide and monitor more personalized treatments for cardiovascular disease (CVD) patients. More...
27 Jun 2017
Image: An illustration of Coll2-1, a marker specific of type II collagen degradation in osteoarthritis (Photo courtesy of Artialis).

Specific Biomarker Assessed for Cartilage Degradation

Osteoarthritis (OA) is one of the most common forms of musculoskeletal disorders and one of the major causes of pain and disability in the adult population. Viscosupplementation is a symptomatic treatment of the knee osteoarthritis based on the intra-articular injection of hyaluronic acid (IAHA). More...
21 Jun 2017
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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