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BioResearch

Image: MIT engineers designed RNA-carrying nanoparticles (red) that can be taken up by endothelial cells (stained blue) (Photo courtesy of Aude Thiriot, Harvard University).

RNA Interference Mechanism May Be Used to Treat Cancer

RNA carried by new nanoparticles can silence genes in many organs, and researchers believe that it could be utilized to treat cancer.  More...
27 May 2014
Image: Stem cells loaded with cancer-killing herpes virus attack a brain tumor cell. Tumor cells in green. oHSV-loaded stem cells in red. oHSV-infected tumor cells in yellow (Photo courtesy of Dr. Khalid Shah, Harvard University).

Stem Cells Loaded with Oncolytic Herpes Virus Destroy Brain Tumors in Mouse Model

Cancer researchers treated mouse models of the human brain tumor glioblastoma multiforme by injecting the animals with stem cells loaded with oncolytic herpes virus and treated virus-resistant tumors with oncolytic herpes viruses genetically engineered to express the proapoptotic cytokine TRAIL.  More...
26 May 2014

Monoclonal Antibody Blocks B-Cell Receptor and Eases Leukemia Burden in Mouse Model

Blocking the B-cell-activating factor receptor on leukemia cells has been suggested as a new approach for treating an acute, chemotherapy-resistant form of childhood leukemia.  More...
26 May 2014

Novel Approach Simplifies Complex Sugars on Protein-Based Biotech Medicines

A team of biotech medicine developers has established a cell-based production method that reduces the complexity of the sugars expressed on protein-based drugs.   More...
25 May 2014
Image: Microscopic view of the engineered bone with an opening exposing the internal trabecular bony network, overlaid with colored images of blood cells and a supportive vascular network that fills the open spaces in the bone marrow-on-a-chip (Photo courtesy of James Weaver, Harvard’s Wyss Institute).

Bone Marrow-on-a-Chip Designed to Evaluate New Drugs, Radiation Toxicity

New organ-on-a-chip technology is providing scientists with an important new tool to assess the effects of new drugs and toxic agents on whole bone marrow.   More...
25 May 2014
Image: Figure A shows the location and angle of the coronary calcium scan image. Figure B is a coronary calcium scan image showing calcifications in a coronary artery (Photo courtesy of the [US] National Heart, Lung, and Blood Institute).

Aspirin Use for Heart Disease Prevention May Benefit Those with Coronary Artery Calcium Deposits

A recent study found that taking aspirin to prevent heart disease benefits individuals with high coronary artery calcium scores but can actually cause damage from bleeding in individuals with low levels of coronary artery calcium.  More...
21 May 2014
Image: Arup and Gitali Indra are beginning to find clues to predicting, preventing and stopping melanoma before it spreads (Photo courtesy of Karl Maasdam / Oregon State University College of Pharmacy).

Melanoma May Be Triggered by Deficit of Retinoid-X-Receptors in Melanocytes

Cancer researchers have linked the development of the deadly skin cancer melanoma to depressed expression in melanocytes of the type II nuclear receptors Retinoid-X-Receptor alpha and Retinoid-X-Receptor beta.   More...
20 May 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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