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BioResearch

Image: Expression of RUNX2 in the nucleus of 1205LU melanoma cells (Photo courtesy of the Rutgers Cancer Institute).

Melanoma Development Depends on the Activity of the RUNX2 Transcription Factor

The transcription factor RUNX2 has been found to play a critical role in melanomagenesis, the processes leading to development of the skin cancer, melanoma.  More...
28 Apr 2014
Image: Cell-like features in computer simulated active droplets: Left – static distortion; Middle – motility; Right: division (Photo courtesy of Dr. Luca Giomi and Dr. Antonio DeSimone, SISSA).

Simulation Gives Clues About Forces Underlying Fundamental Cellular Processes

Researchers have developed a simulation model resulting in clues to physical conditions that help drive cell division and motility. The results may also hint at conditions that helped facilitate the original transition from inanimate to living matter.  More...
28 Apr 2014
Image: The model consists of a grid structure, 10 mm in width and length, made from gelatin, alginate and fibrin, which recreates the fibrous proteins that make up the extracellular matrix of a tumor (Photo courtesy of Institute of Physics (IOP) Publishing).

Cancer Cells 3D Printed to Mimic Tumors

A group of Chinese and American researchers have successfully created a three-dimensional model of a cancerous tumor using a 3D printer.  More...
24 Apr 2014
Image: University of Michigan researchers have found that mechanical forces in the environment of human embryonic stem cells influences how they differentiate, or morph into the body\'s different cell types. To arrive at the findings, they cultured the stem cells on ultrafine carpets made of microscopic posts (Photo courtesy of Ye Tao, Rose Anderson, Yubing Sun, and Jianping Fu).

Silly Putty Component Used to Help in Stem Cell Therapies

The sponginess of the setting where human embryonic stem cells are growing, affects the type of specialized cells they will ultimately become, new research shows.  More...
22 Apr 2014
Image: Biopsy of small bowel showing celiac disease manifested by blunting of villi, crypt hyperplasia, and lymphocyte infiltration of crypts (Photo courtesy of Wikimedia Commons).

Reduced Elafin Levels Associated with Celiac Disease Bowel Inflammation

Levels of the enzyme elafin, an endogenous serine protease inhibitor, were lower in the small intestinal epithelium of patients with active celiac disease as compared to similar tissue from control patients.   More...
22 Apr 2014

A Pair of Gene Splice Isoforms Has Opposite Effects on Cancer Development

Two distinct splice isoforms of the MAP kinase interacting serine/threonine kinase 2 gene have dramatically different roles in cancer development and growth.  More...
21 Apr 2014
Image: New LabElite line of benchtop devices provides automated sample decapping, recapping, and identification (Photo courtesy of Hamilton Storage Technologies).

New Benchtop Devices Provide Automated Sample Decapping, Recapping, and Identification

A new line of benchtop devices provides flexible solutions for sample processing, tracking, and security for automated and manual liquid handling workflows.   More...
20 Apr 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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