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BioResearch

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Pipetting Assistant Helps Prevent Repetitive Strain Injuries

A powerful pipetting accessory makes life easier for technicians in both clinical and research laboratories.  More...
01 Sep 2015
Image: Researchers engineered cultured cells to contain a red marker that moves into the nucleus upon HCV infection. Nothing happened when normal cells were exposed to HCV (top), but when the researchers expressed the protein SEC14L2, some nuclei changed color from blue to purple (bottom) (Photo courtesy of Laboratory of Virology and Infectious Disease at The Rockefeller University).

DNA Found That Enables Growth of Wild-Type Hepatitis C Virus in Cell Cultures

A team of molecular virologists has found that the overexpression of a particular DNA in liver cancer cells enables these cells to maintain the growth of wild-type Hepatitis C virus in culture.  More...
31 Aug 2015
Image: Research headed by Emory University ethnobotanist Dr. Cassandra Quave, shown collecting chestnut leaves in Italy, was inspired by traditional folk remedies (Photo courtesy of Marco Caputo).

Plant Extract Prevents Bacterial Skin Infections by Disrupting Quorum Sensing

An extract prepared from the leaves of the European chestnut Castanea sativa, a stalwart of Mediterranean region folk medicine, has been found to efficiently block the virulent effects of Staphylococcus aureus by preventing toxin production rather than by killing the organism.  More...
30 Aug 2015

MS Drug Deal to Net More Than USD 1 Billion

A pharmaceutical company based in Switzerland has purchased the remaining rights to the multiple sclerosis drug Ofatumumab, which will allow it to continue development of the compound for treating relapsing remitting multiple sclerosis and similar autoimmune diseases.  More...
30 Aug 2015
Image: Liver-on-chip device and microscopic image of bionic liver (Photo courtesy of Dr. Yaakov Nahmias, The Hebrew University of Jerusalem).

Novel Microreactor Enables Evaluation of Drug Toxicity on the Liver

A novel three-dimensional microreactor capable of maintaining metabolically active liver cells in vitro for over 28 days under stable oxygen gradients that mimic the in vivo microenvironment of the liver was used to determine why the painkiller acetaminophen causes damage to this organ.  More...
26 Aug 2015
Image: Researchers used Time-lapse Imaging Microscopy In Nanowell Grids (TIMING) to demonstrate that CD4+ CD19-chimeric antigen receptor (CAR+) T-cells participate in multi-killing of tumor cells with slower kinetics of killing than CD8+CAR+T cells but high motility subgroups of both T-cell subsets have similar kinetics (Photo courtesy of the University of Houston).

Novel Algorithms Allow Automated Monitoring of Individual Cell-to-Cell Interactions

A novel combination of microscopy, time-lapse video recording, and analytical algorithms enables tracking of individual cell-to-cell interactions, which will boost research towards cancer immunotherapy treatments.  More...
25 Aug 2015
Image: Skin cells (keratinocytes) treated with an agent that activates TLR3 (dsRNA) can turn on important regeneration proteins, like Wnt7b (green) (Photo courtesy of Johns Hopkins University).

Molecular Pathway Leads to Skin and Hair Regeneration After Injury

The ability of the skin to regenerate after injury has been linked to stimulation of Toll-Like Receptor 3 by double-stranded RNA released by the damaged skin.  More...
25 Aug 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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