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BioResearch

Image: At only about 20 nanometers in size and featuring a unique hierarchical structure, 3HM nanocarriers meet all the size and stability requirements for effectively delivering therapeutic drugs to brain cancer tumors (Photo courtesy of Dr. Ting Xu, Lawrence Berkeley National Laboratory).

Novel Nanocarriers Ferry Anticancer Drugs Across the Blood-Brain Barrier

A recent paper described the development of a novel class of highly stable, long-circulating three-helix micelles (3HM) capable of ferrying chemotherapeutic agents across the blood-brain barrier for the treatment of the deadly brain tumor glioblastoma multiforme (GMB).  More...
07 Dec 2015
Image: This rolled-up strip of engineered tissue allows researchers to mimic the way cells grow in a tumor, yet it can be unrolled in seconds for detailed analysis (Photo courtesy of Darren Rodenhizer, University of Toronto Engineering).

Researchers Culture Novel Three-Dimensional Artificial Tumors

A team of Canadian cancer researchers has developed a novel method for growing three-dimensional cultures of cancer cells that behave as artificial tumors and which can be readily resolved to evaluate the response of individual cells to different levels of oxygen and nutrients. More...
07 Dec 2015
Image: Photomicrograph showing examples of individual pacemaker cells (Photo courtesy of Dr. Vasanth Vedantham, University of California, San Francisco).

Advances in Stem Cell Technology Boost Efforts to Develop a Biological Pacemaker

A recent review article summarized the progress being made in the endeavor to develop permanent biological pacemakers to replace the currently used electronic heart pacemakers, which require regular maintenance and periodic replacement.  More...
06 Dec 2015

When Exercise Is Unhealthy: Study Sheds New Light on Sudden Cardiac Death

Researchers have discovered new aspects, involving a mutated protein, of a not-well-understood mechanism that underlies how sudden heart failure can occur during endurance exercise in patients with arrhythmogenic ventricular cardiomyopathy, which currently has no standardized guidelines for exercise management.  More...
06 Dec 2015

Japanese Stem Cell Firm Acquires Scottish Drug Discovery Support Company

In order to facilitate its move into the drug discovery industry, a Japanese stem cell technology company has acquired a Scottish biotechnology company that provides highly characterized human tissues for pharmaceutical development studies.  More...
06 Dec 2015

Ancient Genomes Reveal Natural Selection During Introduction of Farming in Europe

A new study of ancient genomes has tracked evolutionary changes associated with the introduction of agriculture into Europe about 8,500 years ago, finding particular migrations and lifestyle adaptations reflected down to the molecular level of particular genes.  More...
02 Dec 2015
Image: Malaria-vector Anopheles stephensi, the Asian mosquito species that can found from Egypt all the way to China, obtains a blood meal from a human host through its pointed proboscis (Photo Courtesy of Jim Gathany / CDC).

Mosquitoes Genetically Modified as Malaria-Blocking Insect Model

Scientists used CRISPR gene editing to create a parasite-resistant strain of Anopheles mosquito capable of rapidly introgressing malaria-blocking genes into a mosquito population through its progeny, ultimately eliminating the insects’ ability to transmit the Plasmodium falciparum parasite to humans.   More...
02 Dec 2015
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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