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The enzyme-linked immunosorbent assay for estradiol (E2) (Photo courtesy of Calbiotech).

Higher Estrogen Levels Linked to Severe Disease in Scleroderma

 Systemic sclerosis (SSc) is an autoimmune, connective tissue disease of unknown etiology characterized by immune system dysregulation and excessive extracellular matrix (ECM) synthesis. As in most autoimmune diseases, there is a female predominance in SSc with a female to male ratio of 3:1, which increases to 9:1 during childbearing years. More...
19 Jun 2019
Representative histologic features of the small intestine. In the normal duodenal biopsy (A), the villi are elongated and the crypts relatively short. This is in contrast to the small intestinal tissue affected by celiac disease (B), which demonstrates marked villus blunting and crypt hyperplasia. (Photo courtesy of Tracy R. Ediger MD, and Ivor D. Hill, MD ChB).

Biomarker Found for Celiac Patients on Gluten-Free Diet

 Celiac disease is a complex condition, routinely treated by means of a strict gluten-free diet (GFD). One of the diagnostic challenges of this disease is that patients need to be consuming gluten so that a correct diagnosis by means of endoscopy can be made. More...
19 Jun 2019
The Prolisa C. difficile GDH EIA is a microwell assay for the qualitative detection of Clostridium difficile glutamate dehydrogenase (GDH) in fecal specimens. The test is intended for use as an aid in the diagnosis of C. difficile infections (Photo courtesy of Pro-Lab Diagnostics).

NA Amplification Tests for Clostridium Diagnosis Reviewed

 Clostridioides (Clostridium) difficile infection (CDI) is the leading cause of health care-associated infections in the USA. It accounts for 15% to 25% of health care-associated diarrhea cases in all health care settings, with 453,000 documented cases of CDI and 29,000 deaths in the USA in 2015. More...
19 Jun 2019
The Prolisa C. difficile GDH EIA is a microwell assay for the qualitative detection of Clostridium difficile glutamate dehydrogenase (GDH) in fecal specimens. The test is intended for use as an aid in the diagnosis of C. difficile infections (Photo courtesy of Pro-Lab Diagnostics).

NA Amplification Tests for Clostridium Diagnosis Reviewed

 Clostridioides (Clostridium) difficile infection (CDI) is the leading cause of health care-associated infections in the USA. It accounts for 15% to 25% of health care-associated diarrhea cases in all health care settings, with 453,000 documented cases of CDI and 29,000 deaths in the USA in 2015. More...
19 Jun 2019
A new blood test promises near instant diagnosis of a heart attack using a newly discovered protein biomarker (Photo courtesy of iStock).

Novel Blood Test for Myocardial Infarction Tested

 The level cardiac myosin-binding protein C (cMyC) in the blood increase more rapidly after a myocardial infarction, and to a higher extent, than troponin. This means meaning that the new test can rule out a myocardial infarction in a higher proportion of patients straight away. More...
19 Jun 2019
Chagas STAT-PAK assay is a rapid diagnostic test, easy to perform, requires no cold chain storage, uses a minimal sample size, and provides visual detection of antibodies to Trypanosoma cruzi (Photo courtesy of Chembio Diagnostic Systems).

Rapid Tests Assessed for Chronic Chagas Disease

 Chagas disease (CD) is a parasitic disease that can affect seriously the health status of affected individuals. People with CD, mainly living in remote areas of Latin America, often face major barriers to the disease recognition, diagnosis and treatment. In the U.S., there are estimated to be at least 300,000 cases of chronic Chagas disease among people originally from countries of Latin America where Chagas disease is endemic. More...
18 Jun 2019
Breast cancer cells invading through a layer of fibroblasts. Hormone receptor-positive breast cancer has been found to spread faster when the microbiome is disrupted (Photo courtesy of Institute of Cancer Research).

Unhealthy Gut Promotes Spread of Breast Cancer

 Most breast cancers, 65% or more, are hormone receptor positive. That means their growth is fueled by a hormone, either estrogen or progesterone. The good news is that these types of cancers are likely to respond well to hormone therapy. More...
18 Jun 2019
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