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Technology

Image: The SpinDx system (Photo courtesy of Sandia National Laboratories).

Integrated LAMP and Immunoassay Platform Detect Diarrheal Disease

The challenges of diagnosing infectious disease, especially in the developing world, and the shortcomings of available instrumentation have exposed the need for portable, easy-to-use diagnostic tools capable of detecting the wide range of causative microbes while operating in low resource settings. More...
26 Sep 2018
Image: The matrix-assisted laser desorption ionization–time of flight mass spectrometer (Photo courtesy of Bruker Daltonics).

MALDI-TOF MS Used to Identify Pythiosis

Pythiosis is a life-threatening infectious disease caused by the oomycete Pythium insidiosum. The disease has been increasingly reported worldwide and most patients with pythiosis undergo surgical removal of an infected organ. More...
25 Sep 2018
Image: The Q Exactive hybrid quadrupole-orbitrap mass spectrometer (Photo courtesy of Thermo Fisher Scientific).

Residual Tissue Repositories Suitable for MS-Based Proteomics

Mass spectrometry-based proteomics has become a powerful tool for the identification and quantification of proteins from a wide variety of biological specimens. More...
12 Sep 2018
Image: Nucleic acid hybridization on an electrically reconfigurable network of gold-coated magnetic nanoparticles enables microRNA detection in blood (Photo courtesy of University of New South Wales).

Magnetic Nanoparticle Tool Developed to Detect MicroRNA

A magnetic nanoparticle-based technique has been developed to directly detect microRNA (miRNA) in unprocessed whole blood samples in about thirty minutes. Currently scientists use quantitative reverse-transcription polymerase chain reaction (qRT-PCR) to profile miRNA due to its usually high specificity and sensitivity. More...
12 Sep 2018
Image: A simple, paper-based test can quickly identify a falsified or substandard antibiotic (Photo courtesy of John Eisele).

Simple Paper Test Detects False or Substandard Antibiotics

In the developing world, the manufacture and the distribution of substandard, non-legitimate medicines is widespread. It has been estimated that up to 10% of all drugs worldwide could be falsified with up to 50% of those some form of antibiotics. More...
04 Sep 2018
Image: The new Anti-Zika Virus IgAM ELISA kit detects both IgM and IgA antibodies (Photo courtesy of EUROIMMUN).

ELISA kit Offers Enhanced Diagnosis of Zika Virus Infection

An ELISA kit that measures anti-Zika virus antibodies of both the IgM and IgA classes was shown to accurately diagnose the acute phase of the infection even in patients with prior flavivirus exposure. More...
27 Aug 2018
Image: Coherent fluctuation nephelometry analyses microbiological concentrations in urine (Photo courtesy of Medtechnopark).

Coherent Fluctuation Nephelometry Used to Diagnose Bacteriuria

Urinary tract infections (UTI) belong to the most common infectious diseases, making 20% to 49% of all nosocomial infections. For correct UTI diagnosis, the knowledge about the presence of microorganisms in urine is needed and such diagnosis is traditionally carried out by culture methods using solid nutrient media. More...
20 Aug 2018
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