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Microbiology

Image: A Giemsa-stained, thin film blood smear that shows the presence of numerous of ring-form, Plasmodium falciparum trophozoites, with some infected red blood cells (RBCs) harboring multiple organisms (Photo courtesy of Steve Glenn/CDC).

Gene Deletions Affect Rapid Diagnostic Tests for Malaria

Prompt and accurate diagnosis of malaria is crucial for malaria case-management and control and elimination programs. While malaria diagnosis was historically based on symptoms alone, guidelines state that parasite-based diagnosis of malaria should be confirmed before treatment is given. More...
25 Jul 2019
Image: The Multiskan GO microplate spectrophotometer (Photo courtesy of Thermo Fisher Scientific).

Methods Evaluated to Detect Asymptomatic Visceral Leishmaniasis

Visceral leishmaniasis (VL) is caused by Leishmania infantum [synonymous L. chagasi] in the New World or L. donovani in the Old World, VL can be classified as an anthroponotic or zoonotic disease because it is transmitted between humans and others mammals, such as dogs. More...
24 Jul 2019
Image: An immunohistochemical staining IL-17A expression in (A) M. mycetomatis, and (B) S. somaliensis. IL-17A staining was seen as a brown cytoplasmic staining in cells (Photo courtesy of University of Khartoum).

Immune Molecules Expressed Inside Mycetoma Lesions

Mycetoma is a persistent, progressive granulomatous inflammatory disease caused either by fungi or by bacteria. Characteristic of this disease is that the causative agents organize themselves in macroscopic structures called grains. These grains are surrounded by a massive inflammatory reaction. More...
24 Jul 2019
Image: A scanning electron micrograph (SEM) of infectious particles of the avian H7N9 virus emerging from a cell (Photo courtesy of Medical Xpress).

T Cell Antibody and Memory in H7N9 Survivors Characterized

Avian influenza A (H7N9) is a subtype of influenza viruses that have been detected in birds in the past. This particular A (H7N9) virus had not previously been seen in either animals or people until it was found in March 2013 in China. More...
19 Jul 2019
Image: QuantiFERON-TB Gold (QFT) is an innovative blood test that measures the cell-mediated immune response of Mycobacterium tuberculosis infected individuals (Photo courtesy of Qiagen).

TB Tests May Not Detect Infection in Exposed Individual

Mycobacterium tuberculosis is the leading infectious cause of death worldwide Exposure to M. tuberculosis results in heterogeneous clinical outcomes including primary progressive tuberculosis (TB) and latent tuberculosis infection (LTBI). More...
17 Jul 2019
Image: A photomicrograph of an unstained, formalin preserved stool specimen mount, revealed the presence of a Paragonimus westermani trematode egg. Human infections of this lung fluke are most common in eastern Asia and in South America (Photo courtesy of the CDC).

Antibody Tests Recommended for Parasitic Infection Diagnosis

Pleural parasitic infestation (PPI) is a disease prevalent in certain parts of the world and it is frequently misdiagnosed due to its lack of standardized diagnostic criteria. The clinical manifestations are non-specific and many patients are initially treated for tuberculosis or misdiagnosed as lung cancer. More...
16 Jul 2019
Image: Digitally colorized photomicrograph of fluorescent antibody labeled Streptococcus pneumoniae bacteria in spinal fluid sample (Photo courtesy of the CDC).

Nasal Microbiome Influences Pneumonia and Related Diseases

A recent study examined the influence of the natural microbial flora in the nose and viral co-infection on the acquisition of Streptococcus pneumoniae bacteria and the development of pneumococcal diseases. More...
15 Jul 2019
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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