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Molecular Diagnostics

Image: This diagram outlines the dual potential of EV-RNAs in IBD: as non-invasive biomarkers for early diagnosis and monitoring, and as carriers of regulatory RNAs to target inflammation, repair the epithelial barrier, and restore gut homeostasis. (Ruizhe Ren/Zhejiang Chinese Medical University, Xiyang Wei/Sir Run-Run Shaw Hospital, Zhejiang University School of Medicine)

Extracellular Vesicle RNA Biomarkers Enable Noninvasive IBD Diagnosis and Monitoring

EV‑RNA biomarkers show promise for noninvasive monitoring and treatment of inflammatory bowel disease. More...
13 Apr 2026
Image: A prescription kit is mailed directly to a patient’s home for self-collection, with the specimen then returned by mail to a laboratory for processing. (photo courtesy of BD)

FDA Clears At-Home HPV Test with Extended Genotyping for Cervical Screening

A new at-home HPV self-collection kit and extended genotyping assay enable mail-in clinician-ordered cervical screening. More...
13 Apr 2026
Image: Graphical Abstract (Zhuo Wang et al, Cell Reports Medicine (2026). DOI: 10.1016/j.xcrm.2026.102741)

New Gene Signature Reveals Underdiagnosed Lung Cancer Subtype

A new four-gene test flags underdiagnosed combined small-cell lung cancer from routine biopsies. More...
13 Apr 2026
Image: Graphical abstract (The American Journal of Human Genetics (2026). DOI: 10.1016/j.ajhg.2026.02.017)

Genome Sequencing Identifies Noncoding Variants Causing Neonatal Diabetes

Genome sequencing reveals noncoding RNA variants causing autoimmune neonatal diabetes. More...
10 Apr 2026
Image: Findings indicate the ability to stratify individuals by expected weight-loss efficacy of GLP-1 therapies as well as risk for certain side effects (photo courtesy of Adobe Stock)

Genetic Markers Predict GLP-1 Weight-Loss Response and Side Effects

New findings identify GLP1R/GIPR variants predicting GLP-1 weight-loss efficacy and nausea risk, enabling patient stratification. More...
10 Apr 2026
Image: Graphical abstract (Shi W., Liu K., Esfahani M., Cell (2026). DOI: 10.1016/j.cell.2025.12.054)

Noninvasive Urine Test Predicts Recurrence After BCG in Bladder Cancer

A new urine tumor DNA test improves MRD detection in bladder cancer and predicts post-BCG recurrence More...
09 Apr 2026
Photo courtesy of Adobe Stock

Mesothelioma in Younger Adults Linked to Genetic Risk Factors

New data show distinct pleural mesothelioma patterns in younger adults, supporting genetic testing to guide targeted therapy. More...
09 Apr 2026
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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