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Clinical Chemistry

Image: Quanta Master scanning spectrofluorometer (Photo courtesy of Photon Technology International).

Sensor Tracks Zinc in Cells for Prostate Cancer Diagnosis

Mobile zinc is an indispensable component of prostate physiology and the prostate contains more zinc than any other soft tissue in the body, and there is a clear correlation between total prostatic zinc levels and cancer.   More...
31 Dec 2013
Image: Orbitrap Velos Pro hybrid ion trap mass spectrometer (Photo courtesy of Thermo Scientific).

Standardized Assays Developed to Quantify Human Proteins

The feasibility of large-scale standardized protein measurements, which are necessary for validation of disease biomarkers, has been developed.    More...
30 Dec 2013
Image: Micrograph of acute thrombotic microangiopathy disseminated intravascular coagulation (Photo courtesy of Nephron).

Automated Soluble Fibrin Assays Evaluated

The soluble fibrin monomer assay has the potential to be used both as an aid in the diagnosis of disseminated intravascular coagulation and as a thrombotic marker.  More...
26 Dec 2013
Image: Bone marrow aspirate smear from a patient with chronic myelomonocytic leukemia, a myeloproliferative neoplasm (Photo courtesy of M.Yared).

Molecular Test Detects Difficult-to-Diagnose Chronic Blood Cancer

The current blood test used to diagnose blood cancer works by identifying mutation in a specific gene; however, it is not necessary that the gene should be present in every patient.  More...
26 Dec 2013
Image: Triage Placental Growth Factor (PlGF) Test (Photo courtesy of Alere).

Blood Test Predicts Preeclampsia Risk in Pregnant Women

The diagnosis of preeclampsia by using blood pressure and proteinuria is of limited use because they are tertiary, downstream features of the disease.  More...
19 Dec 2013

Evidence Warrants Endometrial Cancer Tumor Testing to Identify Women with Lynch Syndrome

A review of accumulating evidence has led to a strong recommendation to screen all endometrial cancer patients for Lynch syndrome.  More...
18 Dec 2013
Advia 1800 Chemistry Analyzer System (Photo courtesy of Siemens).

Blood Urea and Creatinine Stability Determined for Chemistry Analyzer

Serum creatinine values of patients tend to change as a result of the use of different blanks used for creatinine determinations on some clinical chemistry analyzers.   More...
17 Dec 2013
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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