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Clinical Chemistry

Image: Schematics of protein misfolding cyclic amplification (PMCA) technology for amyloid-β (Aβ) oligomers (Photo courtesy of University of Texas Medical School).

Sensitive Biochemical Method Diagnoses Alzheimer’s Disease

A sensitive method has been used for the biochemical diagnosis of Alzheimer’s disease based on specific detection of misfolded amyloid-β oligomers, which play a central role in AD pathogenesis.    More...
09 Apr 2014
Image: The LTQ-FT Orbitrap XL Hybrid Ion Trap Mass Spectrometer (Photo courtesy of Thermo Scientific).

Proteomic Methods Diagnose Pancreatic Cancer

A method has been developed that identifies pancreatic cancer's visible precursors with 97% certainty, and is expected to aid in the early discovery of the cancer as well as minimize the risk of unnecessary surgery.    More...
08 Apr 2014
Image: The SRI 8610C gas chromatograph (Photo courtesy of SRI Instruments).

Stool Samples Provide Marker for Bowel Disease

A novel method for distinguishing different types of bowel disease using the stool samples of patients has been created which is an ideal noninvasive testing method for the diagnosis of gastro-intestinal diseases.   More...
08 Apr 2014
Image: The Abacus 3CT hematology analyzer, a compact, bench-top, flexible 3-part differential analyzer (Photo courtesy of the Diatron Group).

New Version of 3-Part Differential Hematology Analyzer Launched

A new hematology analyzer is particularly suitable for small laboratories, satellite clinics, and doctors’ offices.   More...
08 Apr 2014
Image: PyroMark CpG Assays predesigned for quantification of CpG methylation by Pyrosequencing (Photo courtesy of Qiagen).

Blood Test Predicts Whether Children Will Become Obese

A simple blood test, which can analyze DNA, could be used to predict obesity levels in children and the test can assess the levels of epigenetic switches in a gene that regulates fat storage in the body.    More...
07 Apr 2014
Image: Model of a molecule of glycated hemoglobin (HbA1c) (Photo courtesy of Molecular Models, Inc.).

Measurement of Glycated Hemoglobin Does Not Aid in Predicting CVD Risk

Determination of levels of glycated hemoglobin does not aid in identifying individuals at risk of developing cardiovascular disease according to a recent study.  More...
07 Apr 2014
Image: Histopathology showing degranulation of eosinophils (pink) with adjacent nerves (brown) in the duodenum of a patient with functional bowel disorder (Photo courtesy of Dr. Marjorie Walker).

Genetic Clue to Irritable Bowel Syndrome Found

Irritable bowel syndrome may be caused by genetics, diet, past trauma, anxiety and all are thought to play a role, but now, for the first time, a defined genetic defect that causes a subset of IBS has been reported.   More...
03 Apr 2014
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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