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Clinical Chemistry

Image: Clostridium difficile colonies grown on cycloserine mannitol agar (Photo courtesy of Janice Carr).

Bacterial Strain Type and Biomarkers Predict Mortality

Clostridium difficile genotype predicts mortality after C. difficile infection, and excess mortality correlates with genotype-specific changes in biomarkers. More...
08 Aug 2013
Image: The FISH-based HPV-associated Cancer Test (FHACT) is a single hybridization assay for the detection of chromosomal regions often observed early in HPV-associated precancers, and as such represent biomarkers of HPV-associated cancer progression (Photo courtesy of Cancer Genetics, Inc.).

Study Confirms Efficacy of New Cervical Cancer Fluorescence Assay

A novel FISH assay that simultaneously detects gains at four chromosomal loci is now available to clinical laboratories for the detection of cancerous and precancerous cervical cells. More...
08 Aug 2013

Blood Test Differentiates Fibromyalgia Syndrome

A finger-stick blood sample test has been developed to detect fibromyalgia syndrome, a painful disorder that is difficult to diagnose. More...
07 Aug 2013
Image: Malaria parasites infect two blood cells (Photo courtesy of Lennart Nilsson).

Clinical Relevance of Biomarkers Evaluated for Malaria

Early diagnosis and risk stratification is important in patients with Plasmodium falciparum malaria for rapid initiation of antimalarial treatment and prevention of complications. More...
31 Jul 2013
Image: API 3000 triple-quadrupole mass spectrometer (Photo courtesy of Applied Biosystems).

Blood Test Determines Reduced and Oxidized Glutathione

Diminished levels of glutathione and the ratio of GSH to glutathione disulfide can serve as important indicators of oxidative stress and disease risk. More...
31 Jul 2013
Image: Histological types are labeled by different colors in the clinical diagnosis and histology expression-predictor tracks. Prediction confidence and stromal score are shaded green to white to blue indicating high to low values. The highest quality predictions exhibit high confidence and low stromal scores (Photo courtesy of the University of North Carolina).

Histology Expression Predictor Assay Eliminates Subjectivity from Lung Cancer Diagnostics

A gene expression-based predictor assay for lung cancer FFPE specimens was able to identify a variety of cancers with accuracy and precision similar to that of microscopic examination by pathologists. More...
29 Jul 2013
Image: The Precision Xceed Pro Blood Glucose and ß-Ketone Monitoring System (Photo courtesy of Abbott Diabetes Care).

Blood Glucose Monitoring System Designed for Accuracy

Recently more attention has been drawn to the accuracy requirements for blood glucose monitoring systems for home use as well as those for hospital use. More...
29 Jul 2013
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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