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Clinical Chemistry

Image: The Polymedco OC auto 80 analyzer (Photo courtesy of Polymedco).

Fecal Immunochemical Test Detects Cancer and Polyps

The most commonly used noninvasive test for colorectal cancer (CRC) screening has been the guaiac fecal occult blood test (gFOBT). The fecal immunochemical test (FIT) detects CRC and colorectal polyps with higher levels of sensitivity than the gFOBT, and may be more acceptable to patients. More...
30 Aug 2017
Image: A rapid diagnostic test for determination of elevated CK-MB levels in blood, which some scientists suggest may be unnecessary (Photo courtesy of Response Biomedical).

Guideline Eliminates Common Test for Diagnosing Heart Attacks

Heart disease remains the leading cause of death in men and women in the USA, and each year 735,000 Americans have heart attacks that damage the heart muscle, and of those, an estimated 120,000 die. More...
30 Aug 2017
Image: A Lone star tick (Amblyomma americanum) that can be carriers of southern tick-associated rash illness (Photo courtesy of Centers for Disease Control and Prevention).

Test Differentiates Lyme Disease from Similar Condition

Lyme disease is the most commonly reported vector-borne illness in the USA, and current laboratory tests are not sensitive enough to detect infection with high accuracy in the first few weeks of illness. In 2015, 95% of confirmed Lyme disease cases were reported from 14 US states. More...
29 Aug 2017
Image: The method uses vibrational microspectroscopic technology, including Fourier Transform Infrared (FT-IR) and Raman laser microspectroscopy, to detect the unique molecular vibrations of different compounds. These vibrations contain information about the sample’s chemical composition, including molecular characteristics, prevalence, and structure (Photo courtesy of Umeå University).

Spectroscopy Reveals Fingerprints for Diabetes Progression

Researchers report a method to study biochemical changes that occur in the pancreas during the development of diabetes. Based on vibrational microspectroscopic technology, the method can be used to extract biochemical profiles containing information about disease progression. This could facilitate improved understanding of key mechanistic processes in diabetes development and manifestation, and could be used to develop better prognostic, diagnostic, and monitoring tools. More...
28 Aug 2017
Image: The epoc POC blood analysis system (Photo courtesy of Alere).

Capillary Blood Analysis Validated for POC System

The gold standard samples for blood gas analysis are arterial blood collected from arterial catheter or by arterial puncture, but the proper sampling of arterial blood is difficult, painful, and sometimes risky to obtain in patient in transport. More...
22 Aug 2017
Image: The Brahms Kryptor automated immunoassay platform (Photo courtesy of Thermo Fisher Scientific).

Immunoassay Biomarkers Evaluated for Preeclampsia Diagnosis

Preeclampsia is one of the leading hypertensive disorders in pregnant women worldwide and it is estimated to cause more than 60,000 deaths per year. Preeclampsia is induced by placental and maternal vascular dysfunction, which affects both maternal and neonatal health. More...
17 Aug 2017
Image: Various blood collection tubes for use in the clinical laboratory (Photo courtesy of Labs USA).

Trends in Metabolites Predict Mortality for Hospitalized Patients

Patients who are hospitalized for an extensive period are at risk for adverse outcomes and are likely to have a high mortality rate than those who have shorter stays. More...
17 Aug 2017
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.

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