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BioResearch

Blocking Breakdown of Norepinephrine Protects Against Heart Failure

The breakdown of the neurohormone norepinephrine by the mitochondrial enzyme monoamine oxidase-A results in production of hydrogen peroxide and other dangerous chemical species that accumulate in the nerves and the heart muscle. More...
14 Jan 2010

Novel Two-Phase Nanoparticles Readily Diffuse Through Mucus

A recent paper described the development of a novel two-phase biodegradable nanoparticle system that readily allows drugs to be delivered through mucus layers into target tissue. More...
13 Jan 2010

Blocking an Interleukin-8 Receptor Reduces Breast Tumor Size and Prevents Metastasis

Blocking the receptor for interleukin-8 on cancer stem cells leads to significant reduction in the size of breast tumors and prevents metastasis. More...
13 Jan 2010

Inhibition of COX-2 Slows Skin Cancer Growth

Reducing expression of the enzyme COX-2 either by genetic engineering or through specific drug inhibition was found to slow growth of the most common form of skin cancer, skin basal cell carcinoma. More...
12 Jan 2010
Image: Colored scanning electron micrograph (SEM) of a freeze-fractured section through the colon wall of a patient suffering from colon cancer (Photo courtesy of Steve Gschmeissner / SPL).

Computer Modeling Predicts Drug Target for Treatment of Epithelial Tumors

A computerized modeling system has been used to identify a potential target for chemotherapy that exists in a wide variety of epithelial tumors. More...
11 Jan 2010

Mutated Muscle Glycoprotein Key to Understanding Muscular Dystrophy

Mutations that change the binding properties of the muscle protein dystroglycan are an underlying cause of several types of muscular dystrophy. More...
11 Jan 2010

Future of Genomic Sciences May Be Large-Scale Sequencing

Scientists are gaining insights into new ways to utilize microorganisms in medicine and manufacturing through a coordinated large-scale effort to sequence the genomes of not just individual microorganisms but entire ecosystems. More...
08 Jan 2010
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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