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BioResearch

Image: A molecular ribbon structure of prostate-specific membrane antigen (PSMA) (Photo courtesy of Wikimedia Commons).

Immunotherapy Slows Tumor Growth in Prostate Cancer Model

Cancer researchers have developed a novel immunotherapy technique based on synthetic DNA plasmids that successfully controlled tumor growth and prolonged survival in a mouse prostate cancer model. More...
01 Sep 2017
Image: A micrograph showing peroxisomes in rat neonatal cardiomyocytes (Photo courtesy of Wikimedia Commons).

Novel Antimicrobial Role of Intracellular Organelle

A recent study illustrated the importance of cellular organelles called peroxisomes to the ability of macrophages to internalize and destroy pathogenic microorganisms through phagocytosis. More...
30 Aug 2017
Image: A molecular model of Takinib, a drug-like molecule that modulates the TNF-alpha inflammatory response, which is at the center of a variety of diseases (Photo courtesy of Duke University).

X-ray Study Explains How Takinib Inhibits TNF-alpha

Takinib, a selective TAK1 inhibiting drug, has been shown to broaden the therapeutic efficacy of TNF-alpha (Tumor necrosis factor-alpha) inhibition for treating cancer and autoimmune diseases. More...
29 Aug 2017
Image: A scanning electron micrograph (SEM) of a gold nanostar. The nanostar\'s size caused it to accumulate within tumors, where researchers used infrared light to heat it and destroy cancerous growths (Photo courtesy of Dr. Tuan Vo-Dinh, Duke University).

Combined Approach Cures Bladder Cancer in Model

A novel anticancer "photothermal immunotherapy" technique that used lasers and gold nanostars to heat up and destroy tumors in combination with an immunotherapeutic drug cured and immunized mice against bladder cancer in a small proof-of-concept study. More...
28 Aug 2017

Stem Cell Therapy Restores Youthful Heart Performance

Cardiac disease researchers have demonstrated in a rat model that injections of cardiosphere-derived cells from young rats could rejuvenate the hearts of aged animals. More...
24 Aug 2017
Image: In this model, the complex sugar molecule (colored) attaches to the tumor protein galectin-1, which is shown in black and white (Photo courtesy of Workgroup Seibel, VCH-Wiley).

Study Details Interaction between Galectin-1 and Carbohydrate Ligands

A team of German researchers used advanced X-ray crystallography techniques to develop a structural understanding of the interaction between the galectin-1 protein and its carbohydrate ligands. More...
23 Aug 2017
Image: Two types of progenitor cells from dissociated skin – epidermal (green) and dermal (red) – undergo a series of morphological transitions to form reconstituted skin (Photo courtesy of Mingxing Lei / Cheng-Ming Chuong Lab).

Molecular Manipulation Induces Skin Cells to Produce Hair

Working with mouse skin cells, researchers have generated hair-producing follicles from newborn and adult cells and traced the molecular pathways that control their development. More...
22 Aug 2017
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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