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BioResearch

Affitoxin Destroys HER2-Positive Tumors in Mouse Trial

A paper disclosed that “Affitoxin,” a novel protein that combines HER2-specific “Affibody” molecules and a modified bacterial toxin, PE38, was an effective anticancer agent in a mouse xenograft model and a potential candidate for clinical studies. More...
10 Aug 2011
Image: Three-dimensional live imaging of zebrafish (upper panel) and fruit fly embryos (lower panel) with two-photon light sheet microscopy. The upper panel shows not only the embryo's tissue (in white) but also green fluorescent protein driven by a gene-specific promoter (in orange). The lower panel shows the individual cell nuclei of the fruit fly embryo, labeled with green fluorescent protein, imaged at different time points during its embryonic development (Photo courtesy of Willy Supatto, Seth Ruffins, Thai Truong / Caltech).

Biologic Images Made Clearer, Deeper, and Faster

For biologists, the ability to capture high-quality, 3D images of living tissues or organisms over time is necessary to answer problems in areas ranging from genomics to neurobiology and developmental biology. More...
10 Aug 2011

New Tools Permit Delicate Manipulation of the Stem Cell Genome

Researchers have compared the effectiveness of two methods for modifying the genomes of human embryonic stem cells and induced pluripotent stem cells. More...
09 Aug 2011

Development Fund to Boost Search for Drugs to Modulate Nuclear Hormone Receptors

A project to develop novel small molecule retinoic acid related orphan receptor modulators that target TH17 T-lymphocytes for the treatment of various autoimmune disorders will be funded by a consortium of private investors. More...
09 Aug 2011
Image: The xCELLigence RTCA MP Instrument (Photo courtesy of Roche).

First Human Kinome Screen Performed on High-throughput Cell Analyzer

A high-throughput cell analysis system has been adapted to perform a human kinome screen based on small interfering RNA transfections. More...
08 Aug 2011

The First European Lab Automation Conference Receives Rave Reviews

The first European scientific conference dedicated to advances in laboratory automation was given high marks by both participants and exhibitors. More...
08 Aug 2011

Rabbit Monoclonal Antibodies Now Available for Use in Cancer-Related Research

Cancer researchers now have access to 23 novel, cancer-related rabbit monoclonal antibodies that have been released to the commercial market. More...
08 Aug 2011
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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