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Image: Left: Quantitative phase image of an unstained prostatectomy sample from a patient who had a biochemical recurrence of prostate cancer. Right: A zoomed-in region from the quantitative phase image showing a cancerous gland with debris in the lumen. The stroma, or supportive tissue environment, shows discontinuities in the fiber length and disorganization in the orientation of the fibers (Photo courtesy of the University of Illinois).

Pathologists Use Spatial Light Interference Microscopy to Predict Risk of Prostate Cancer Recurrence Prior to Biopsy or Surgery

A novel microscopy method that combines phase contrast microscopy with holography enables prediction of the likelihood of prostate cancer recurrence prior to biopsy or surgery.  More...
24 May 2015
Image: A user calibrates a newly developed portable polarimetric fiber stress sensor device while studying tumors by measuring Young’s modulus—an elasticity-related property recently linked to cancerous tumor aggressiveness (Photo courtesy of Kelvin Kuo, University of Southern California).

Portable Device Could Test for Physical Property of Tumor Aggressiveness

A new polarimetric fiber stress sensor device has been developed for visco-elastic and biomimetic material analysis, and, as part of the emerging field of physical oncology, is being tested for measuring a tumor’s Young’s modulus—an elasticity-related measure recently linked to cancerous tumor aggressiveness.  More...
24 May 2015
Image: The measuring channel that forms the key component of the PoCyton cytometer is visible on the right-hand side of the image (Photo courtesy of Fraunhofer ICT-IMM).

Automatic Cytometer Tallies Tumor Cells in Blood

Flow cytometry has been used to count cancer cells for many years, but the large instruments are expensive and can only be operated by trained personnel.  More...
19 May 2015
Image:  The AnemoCheck point-of-care test for hemoglobin (Photo courtesy of Erika Tyburski).

New Point of Care Test for Anemia Developed

New diagnostic technology may shift some hemoglobin testing for anemia out of clinical laboratories and into near-patient settings and it may also be possible to use this new diagnostic device for patient self-testing.  More...
19 May 2015
Image: Color-in chemistry—a novel set of “reagent pencils” applies coloring-book approach that offers a new option for simple, customized point-of-care diagnostics and other chemical testing applications (Photo courtesy of Mitchell HT et al., 2015, and the journal Lab on a Chip/RSC).

Innovative Chemistry Set Applies Coloring-Book Approach to Perform Life-Saving Tests

Scientists have developed a set of “reagent pencils” for solvent-free deposition of reagents onto paper-based microfluidic devices that offers a new option for simple, customized point-of-care diagnostics, and other chemical testing applications.  More...
18 May 2015
Image: A prototype model of the AcµRay point-of-care diagnostic device (Photo courtesy of Emory University).

Novel Point-of-Care Diagnostic Device Performs Several Tests from a Single Sample Preparation

A prototype model of a portable multipurpose point-of-care diagnostic analyzer was used in proof-of-principle studies that established the potential usefulness of this type of instrument.  More...
12 May 2015
Image: Mobidiag’s innovative multiplex diagnostic tests use well-established qPCR technology (Photo courtesy of Mobidiag Ltd.).

New Analytical Systems to Ease Molecular Diagnostic Burden

Two advanced molecular diagnostic systems were introduced at a recent pan-European scientific conference. More...
04 May 2015
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LabMedica's Lab Technology channel informs on laboratory medicine techniques, while keeping an eye on new hardware, LIM software, consumables, and lab trends, techniques and safety.
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