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Technology

Image: The Vivascope 2500 confocal scanning microscopic view of lymph node metastases from thyroid carcinoma are papillary structures made up of scanty bright spots floating in a dark background (left) (Photo courtesy of IRCSS Santa Maria Nuova Hospital).

Confocal Fluorescence Microscopy Used for Rapid Tissue Evaluation

Optical imaging techniques are currently available for imaging tissues without the need for any type of extensive tissue preparation. There are several applications for their potential use in surgical pathology practice. More...
16 Apr 2018
Image: The Malaria Ag P.f test is 10 times more sensitive than current malaria rapid diagnostic tests for the detection of Plasmodium falciparum HRP-II antigen (Photo courtesy of Alere).

Ultra-Sensitive Rapid Test Evaluated for Malaria

In low prevalence regions, subpatent Plasmodium falciparum malaria infections have become an issue of increasing concern. As malaria endemic countries shift from control to elimination, the proportion of low-density P. falciparum infections increases. More...
05 Apr 2018
Image: Two Cholkit dipsticks showing characteristic negative (left image) and positive (right image) results after 15 minutes sample run (Photo courtesy of International Centre for Diarrhoeal Disease Research).

New Dipstick Rapidly Detects Cholera in Acute Diarrhea

Cholera is an acute watery diarrheal disease caused mainly by Vibrio cholerae serogroup O1 and less commonly by V. cholerae O139. Cholera can lead to severe diarrhea and death if untreated. More...
29 Mar 2018
Image: The Lab-on-a-Chip system used with Raman spectroscopy to identify antibiotic resistance (Photo courtesy of Leibniz-Institute of Photonic Technology).

New Rapid Test Reports Antibiotic Resistance in Two Hours

Resistant bacteria are spreading worldwide, which makes fast antibiotic susceptibility testing and determination of the minimal inhibitory concentration (MIC) urgently necessary to select appropriate antibiotic therapy in time. More...
28 Mar 2018
Image: New cutting edge technology can be used to grade cancer tumors, eradicating human subjectivity. A traditional stained H+E biopsy (L) and a Digistain view (R) (Photo courtesy of Imperial College London).

Cutting Edge Technology Used to Grade Cancer Tumors

Biopsy specimens are processed into formalin-fixed-paraffin-embedded (FFPE) blocks and currently, hematoxylin and eosin (H + E) stained sections are widely used for the histopathological diagnosis of cancer and other pathologies. More...
28 Mar 2018
Image: The μCENSE chip with the benchtop centrifugal platform in the background (Photo courtesy of Dr. Joo Chuan Yeo, PhD).

Liquid Biopsy Platform Isolates Circulating Disease Biomarkers

A new platform has been created with the potential to extract tiny circulating biomarkers of disease from patient blood. This simple, fast and convenient technique could help realize liquid biopsy diagnostics, which is a less invasive procedure than the current gold standard tumor biopsies. More...
19 Mar 2018
Image: A new technique that makes tuberculosis bacteria glow detects living Mycobacterium tuberculosis cells that have not been treated with drugs (left) but not those that have been treated (right) (Photo courtesy of Stanford University).

Solvatochromic Trehalose Probe Rapidly Detects TB

Despite its devastating toll on health, the bacteria causing tuberculosis (TB), Mycobacterium tuberculosis, can be hard to spot. Current tests rely on chemical stains and estimates put the sensitivity of these stains anywhere from 32% to 94%. More...
13 Mar 2018
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