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Microbiology

Image: A micrograph of esophageal candidiasis showing hyphae. Biopsy specimen stained by periodic acid-Schiff procedure (PAS stain) (Photo courtesy of Wikimedia).

Review Provides Insight into Therapeutic Interventions

A new review has outlined recommendations and a gold standard for identifying at-risk patients who are critically ill, or in receipt of organ transplants, for preventing, diagnosing and treating invasive fungal infections. It was published as part of a set of papers intended to provide new insights into the breadth of serious fungal diseases and as a call to world health bodies to prevent millions of infections each year. More...
21 Aug 2017
Image: A bioplasmonic paper-based device (BPD) for the detection of Zika virus (ZIKV) infection, via quantification of serum anti-ZIKV-nonstructural protein 1 (NS1) IgG and IgM (Photo courtesy of James Byard).

Biosensor Device Developed for Zika Diagnosis

A novel plasmonic biosensor-based detection system was developed that can diagnose recent or current Zika virus (ZIKV) infection in 15 minutes or less. More...
21 Aug 2017
DIASOURCE (A Biovendor Company)
Image: The VITEK MS, MALDI-TOF1 Mass Spectrometry System, an automated microbial identification system (Photo courtesy of bioMérieux).

Expanded Pathogen Identification Receives FDA Clearance

Mycobacteria, Nocardia and molds are complex organisms to identify, requiring days or weeks of specific culture conditions for appropriate growth and subsequent advanced methods for reliable identification to the species level. More...
15 Aug 2017
Image: The automated ELISA instrument (Photo courtesy of Dynex Technologies).

Three Commercial Tests for Lyme Borreliosis Evaluated

The recommended approach for the diagnosis of Lyme borreliosis consists of screening for Borrelia-specific serum antibodies with an enzyme-linked immunosorbent assay (ELISA), followed by immunoblot confirmation of equivocal or positive ELISA results. More...
15 Aug 2017
Image: In the retrospective cohort study, fluoroquinolone resistance mutation detection assay was found to be equivalent to culture-based drug sensitivity testing in predicting multidrug-resistant tuberculosis treatment outcome (Photo courtesy of Harvard Medical School).

Molecular Tests Predict TB Treatment Outcome

New molecular tests are gaining popularity as a rapid way to detect genetic mutations that render tuberculosis (TB) impervious to drugs. Yet, how well these new tests fare in gauging risk of actual drug failure has remained unclear. Researchers have now found that molecular tests that detect resistance to the fluoroquinolones class of TB drugs may be at least as good as traditional drug-sensitivity tests conducted with lab cultures. More...
14 Aug 2017
Image: The FilmArray respiratory panel enables rapid and accurate automated detection of pathogens causing respiratory infections (Photo courtesy of Idaho Technologies).

Test Discriminates Between Viral and Bacterial Infections

Lower respiratory tract infection (LRTI) commonly causes hospitalization in adults but because bacterial diagnostic tests are not accurate, antibiotics are frequently prescribed. Antibiotics are lifesaving drugs, but overuse is leading to antibiotic resistance, one of the world's most pressing health threats. More...
10 Aug 2017
Image: The Professional Standard TRIO thermal cycler provides three independent 48 well blocks and heated lids in one housing (Photo courtesy of Biometra).

Methods Compared for Chagas Disease Diagnosis

Chagas Disease (CD) is a chronic infectious disease caused by the protozoan flagellate Trypanosoma cruzi. In endemic countries, CD is transmitted mainly through the contact with feces of different triatomine bugs. Due to increased migration, CD has become an international health problem. More...
08 Aug 2017
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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