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Microbiology

Image: Using advanced biochemical analysis of patient serum, researchers found signatures that help predict which patients are at highest risk of dying from S. aureus bacteremia, a blood infection (Photo courtesy of University of California, San Diego)

Proteomics-Based Diagnostic Test Predicts Risk of Dying from Staphylococcus aureus Bacteremia

A diagnostic approach that integrates proteomic and metabolomic techniques enabled the identification of biomarkers that could predict which patients had the highest risk of dying from Staphylococcus aureus bacteremia. More...
14 Sep 2020
Image: Schematic diagram of the immunoassay based on proximity extension assay (PEA) technology (Photo courtesy of Olink Proteomics).

Six Biomarkers Predict Severity of COVID-19

Coronavirus disease 2019 patients admitted to the ICU have high mortality. The host response to coronavirus disease 2019 has only been partially elucidated, and prognostic biomarkers have not been identified. More...
08 Sep 2020
Image: Visualization of Loopamp Trypanosoma cruzi results by the naked eye, Tubes 1 (Negative control) and 5 were negative, but #5 was positive on qPCR with a very low DNA load (Photo courtesy of Laboratorio de Biología Molecular de la Enfermedad de Chagas).

Loop-Mediated Isothermal Amplification Kit Detects Chagas Disease

Chagas disease (CD), also known as American trypanosomiasis, is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi that affects about six to seven million people worldwide, mainly in endemic areas of 21 Latin American countries. More...
07 Sep 2020
Image: A mobile phone app called HandLens was designed to read and report paper strip SHERLOCK results (Photo courtesy of Anna Lachenauer, Stanford University School of Medicine)

Rapid CRISPR/Cas Assay for Diagnosis of Viral Fevers in Low-Tech Environments

Rapid diagnostic tests for Ebola and Lassa fever viruses based on the RNA-targeting CRISPR/Cas13a complex have been tested successfully under field conditions in several African countries. More...
07 Sep 2020
Image: A blood film with a normal mature lymphocyte with a single large nucleus is seen on the left, compared to two segmented neutrophils on the right with multiple nuclear lobes. The lymphocytes are decreased in comorbid diabetes and COVID-19 patients (Photo courtesy of Ed Reschke).

Lymphocyte Count Correlated to Comorbid Diabetes and COVID-19

The coronavirus disease (COVID-19) that erupted in China since December 2019 and has gradually spread throughout the world. At present, it has caused tens of thousands of deaths, and the efficacy of certain antiviral drugs is still under review. More...
03 Sep 2020
Image: The FilmArray GI Panel tests for common gastrointestinal (GI) pathogens including viruses, bacteria and protozoa that cause infectious diarrhea. The integrated FilmArray system brings sample to results in about an hour, with only two minutes of hands-on time (Photo courtesy of Biofire).

Traveler's Diarrhea Among Soldiers Linked to Gut Microbiome Changes

Travelers’ diarrhea (TD) is the most prevalent illness encountered by deployed military personnel and has a major impact on military operations, from reduced job performance to lost duty days. Frequently, the etiology of TD is unknown and, with underreporting of cases, it is difficult to accurately assess its impact. More...
26 Aug 2020
Image: The Genie III instrument was used for the reverse transcriptase loop-mediated isothermal amplification-assay called N1 gene Single Tube Optigene LAMP (N1-STOP-LAMP) for COVID-19 (Photo courtesy of OptiGene Ltd).

Loop-Mediated Isothermal Amplification-Assay Rapidly Diagnoses COVID-19

The SARS-CoV-2 (COVID-19) pandemic of 2020 has resulted in unparalleled requirements for RNA extraction kits and enzymes required for virus detection, leading to global shortages. This has necessitated the exploration of alternative diagnostic options to alleviate supply chain issues. More...
25 Aug 2020
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The LabMedica Microbiology channel provides the latest news in the fields of epidemiology, bacteriology, virology, and parasitology, all viewed from the unique perspective of Laboratory Medicine.
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