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Immunology

Image: The QuickPlex SQ120 utilizes MSD’s proprietary multi-array technology to provide significantly increased sensitivity and dynamic range over standard ELISA with the added benefit of multiplexing (Photo courtesy of Meso Scale Discovery).

Persistent Fatigue Induced by Interferon-Alpha

Chronic fatigue syndrome (CFS), or myalgic encephalomyelitis (ME), is a mysterious condition. The main symptom of CFS is extreme and often unrelenting fatigue; others include muscle and joint pain, sleep issues, and flu-like symptoms. More...
21 Jan 2019
Image: Photomicrograph of Acid-fast Ziehl-Neelsen Staining of Mycobacterium tuberculosis in a sputum smear (Photo courtesy of Rockefeller University).

Genetic Mutation Identified for TB Vulnerability

About one in five people worldwide are infected with Mycobacterium tuberculosis, the bacterium that causes tuberculosis. Of those, only 10%, at most, will show symptoms, because most immune systems have tools to fight the microbe. When these tools are absent or dysfunctional, however, the infection can damage the lungs and other organs, and even cause death. More...
15 Jan 2019
Image: The Calprolab enzyme-linked immunosorbent assay (ELISA ALP) test kit for calprotectin estimation (Photo courtesy of Calpro).

Calprotectin Independently Predicts Relapse in Treated RA

Calprotectin is a biomarker of disease activity in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) and predicts relapse in juvenile idiopathic arthritis. Higher drug trough serum levels are associated with a good response in patients treated with tumor necrosis factor inhibitors (TNFi). More...
14 Jan 2019
Image: The BN II Nephelometer System is an easy-to-use, reliable nephelometric analyzer that offers a broad range of protein assays (Photo courtesy of Siemens Healthcare).

Urinary Biomarkers Associated with Kidney Disease Risk Factors

The improved life expectancy among treated human immunodeficiency virus (HIV)-positive patients has been tempered by the excess burden of age-related non-infectious co-morbidities, including chronic kidney disease (CKD). More...
14 Jan 2019
Image: PLATEILA DENGUE NS1 AG: Qualitative or semi-quantitative detection of dengue virus NS1 antigen in human serum or plasma by enzyme immunoassay (Photo courtesy of Bio-Rad).

Dengue Virus IgM Serotyped by ELISA

Dengue virus (DENV) is an arthropod-borne flavivirus that is endemic in tropical and subtropical regions, causing hundreds of millions of infections annually. It is subdivided into four serotypes, DENV-1–4. After infection, patients have lifelong immunity against the homologous serotype but remain susceptible to infections with the others. More...
03 Jan 2019
Image: SureSelect Target Enrichment Systems (Photo courtesy of Agilent Technologies).

Genetic and Epigenetic Features Found in Glioma Tumors

Neurofibromatosis type 1 (NF1) is a multisystem genetic disorder that is characterized by cutaneous findings, most notably café-au-lait spots and axillary freckling, by skeletal dysplasias, and by the growth of both benign and malignant nervous system tumors, most notably benign neurofibromas. More...
27 Dec 2018
Image: The Simoa HD-1 Analyzer is a fully automated instrument for running immunoassays (Photo courtesy of Quanterix).

Urinary Biomarkers for Tuberculosis Explored

The gold standard for tuberculosis (TB) diagnosis is the isolation in culture of Mycobacterium tuberculosis in biological samples. However, culture is time consuming and does not accomplish the need of quickly and properly starting treatment, it is not always feasible in extra-pulmonary TB and it is difficult to carry out in resource-limited settings. More...
25 Dec 2018
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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