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Molecular Diagnostics

Image: Human males have a single copy of the X-chromosome (Photo courtesy of the University of North Carolina).

Novel X-Linked Intellectual Disability Genes Identified

A novel group of genes on the X-chromosome that when mutated lead to the mental disorder X-linked intellectual disability have been added to list of more than a 100 such genes that had been identified previously.  More...
24 Feb 2015
Image: Photomicrograph of a bone marrow biopsy from a patient with aplastic anemia; hematopoietic elements are markedly reduced (Photo courtesy of the University of Utah).

Transplanted Blood Cell Biomarker Associated with Improved Survival

Among patients with severe aplastic anemia who received stem cell transplant from an unrelated donor, longer leukocyte telomere length, a structure at the end of a chromosome was associated with increased overall survival at five years.  More...
23 Feb 2015
Image: A completely hatched blastocyst of high quality for in vitro fertilization (Photo courtesy of Dr. Richard Sherbahn MD).

Whole Genetic Code of IVF Embryos Scanned for Mutations

Currently, the methods available for preimplantation genetic diagnosis of in vitro fertilized embryos do not detect de novo single-nucleotide and short indel mutations, which have been shown to cause a large fraction of genetic diseases.  More...
23 Feb 2015
Image: QX100 Droplet Reader for Droplet Digital PCR system (Photo courtesy of Bio-Rad).

Simple Method Monitors β-Cell Death in Type 1 Diabetes Individuals

The β-cell killing that characterizes type 1 diabetes is thought to begin years before patients present clinically with metabolic decompensation; however, this primary pathologic process of the disease has not been measured.  More...
17 Feb 2015
Image: Histopathology of chondrosarcoma of the chest wall from surgical resection of recurrent mass (Photo courtesy of KGH/Wikipedia).

Blood Test Developed for Aggressive Bone Cancer

A simple blood test has been developed to diagnose bone cancer, specifically Chondrosarcoma, an extremely unpredictable form of bone cancer that can develop at any age.   More...
17 Feb 2015
Image: Three dimensional structure of apolipoprotein E (APOE) (Photo courtesy of the Protein Data Bank).

Simple Blood Test Can Predict Dementia Risk

A new biomarker has been identified that can predict the risk of developing dementia by way of a simple blood test which in the long term could mean better prevention and at least postponement of the illness and at best evading the development all together.  More...
16 Feb 2015

Potential Biomarkers for High-Risk Colon Cancer Discovered

A new study has discovered unique metastasis-specific microRNA signatures in primary colorectal cancers that could predict prognosis and distant metastasis, helping physicians suggest more effective therapies.  More...
08 Feb 2015
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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