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BioResearch

Image: Muscle cells are stained green in this micrograph of cells grown from embryonic stem cells. Cell nuclei are stained blue; the muscle fibers contain multiple nuclei. Nuclei outside the green fibers are from non-muscle cells (Photo courtesy of Dr. Masatoshi Suzuki, University of Wisconsin).

Novel Culture Technique Generates Large Numbers of Functional Human Muscle Cells

A novel technique that uses free-floating spherical culture in a defined, serum-free culture medium generated large numbers of functional muscle cells from human embryonic stem and induced pluripotent stem cells.   More...
30 Mar 2014

Bacterium Induced to Resist Radiation Damage in the Lab

By exploiting the ability of an organism to evolve in response to punishment from a hostile environment, scientists have coaxed the bacterium Escherichia coli to drastically resist ionizing radiation, and at the same time, reveal the genetic mechanisms that make the feat possible.   More...
30 Mar 2014
Image: Micrograph showing amyloid-beta (brown) in senile plaques of the cerebral cortex (upper left of image) and cerebral blood vessels (right of image) with immunostaining (Photo courtesy of Wikimedia Commons).

Cathepsin B Inhibitors Ease Alzheimer's Symptoms by Blocking Amyloid Plaque Formation

Neurobiologists studying the molecular processes underlying Alzheimer's disease have identified the mechanism that explains how inhibition of cathepsin B activity blocks formation of the toxic amyloid-beta peptides that characterize the disease.  More...
27 Mar 2014
Image: Schematic diagram of the Epstein-Barr virus (Photo courtesy of Wikimedia Commons).

Viral Oncogenes Short-Circuit Critical DNA Repair Mechanisms

A team of molecular biologists has used the oncogenic Epstein-Barr virus to determine how DNA repair mechanisms become compromised to allow cells with damaged genomes to divide and proliferate.  More...
27 Mar 2014
Image: LIMD2, a protein that can drive metastasis (Photo courtesy of the Wistar Institute).

Metastasis Drug Target Identified

Cancer researchers have identified a protein that is critically linked to processes leading to metastasis, the deadly spread of cancer away from the primary tumor.  More...
26 Mar 2014
Image: Insulin-expressing cells (red) arising within the intestinal crypts (green) of a mouse that received three beta-cell “reprogramming factors” (Photo courtesy of Dr. Ben Stanger, University of Pennsylvania).

Transformed Intestinal Cells Produce Insulin in Novel Diabetes Treatment

A population of intestinal cells was found to be capable of morphing into insulin-producing beta-cells, which may pave the way a novel treatment for diabetes.  More...
25 Mar 2014
Image: The structure of the ATP-triggered nanoparticle (left) and how the nanoparticles shrink a tumor (right) (Photo courtesy of North Carolina State University).

ATP-Triggered Nanoparticles Effectively Kill Breast Cancer Cells in Mouse Model

A recent paper describes novel nanoparticles that transport toxic anticancer drugs specifically to tumor cells where they are engulfed and induced to release their cargo by the high intracellular concentration of adenosine-5'-triphosphate.  More...
25 Mar 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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