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BioResearch

Image: Progressively spaced micropillars highlight the new magnetic ratcheting cell sorting system (Photo courtesy of University of California, Los Angeles).

Researchers Reveal a Microchip Magnetic Cell Sorting Device

A novel magnetic cell sorting system may potentially be reduced in size for development into a "lab-on-a-chip" device.  More...
07 Mar 2016
Image: Micrograph of pancreatic ductal adenocarcinoma—the most common type of pancreatic cancer (Photo courtesy of Wikimedia Commons).

Loss of a Specific MicroRNA Leads to Growth and Spread of Pancreatic Cancer

Cancer researchers have found that the loss of a specific microRNA enables pancreatic cancer cells to avoid the tumor suppressor pathways that induce senescence and induces them go grow and spread.  More...
07 Mar 2016
Image: Microglia (green) surround an amyloid plaque (blue) in the brain of an Alzheimer\'s disease mouse model. Endogenous mouse antibodies (red) associate with microglia in the brains of such mice and boost the microglia\'s ability to degrade plaques (Photo courtesy of Dr. Samuel Marsh, University of California, Irvine).

Neurological Disease Researchers Confirm Link Between Adaptive Immune System and Alzheimer's Disease

Using a novel immunodeficient mouse model that they had created, a team of neurological disease researchers demonstrated the link between the adaptive immune system and the development of Alzheimer's disease.  More...
06 Mar 2016
Image: Entry of coronaviruses into cells is mediated by the transmembrane spike glycoprotein S, which forms a trimer, which carries receptor-binding and membrane fusion functions (Photo courtesy of Veesler Laboratory, University of Washington).

Structural Analysis Reveals Potential Coronavirus Vaccine Targets

High-resolution analysis of the coronavirus spike glycoprotein has revealed common binding, fusion, and antigenic sites that may be exploited for the development of a broad spectrum vaccine against this family of viruses that includes the human pathogens SARS-CoV and MERS-CoV.  More...
06 Mar 2016
Image: Pluristem technicians produce PLacental eXpanded (PLX) cells in the company's state-of-the-art facility (Photo courtesy of Pluristem Therapeutics).

Projects Promote Use of Placental Cells in Bone Marrow Disorder Therapeutics

An Israeli biotechnology company will be collaborating with Japanese researchers and American health authorities to complete development of a novel cell-based therapeutic approach for treatment of Acute Radiation Syndrome and other conditions that prevent the bone marrow from making new blood cells.  More...
06 Mar 2016
Image: Structure of normal frataxin (FXN) protein (Photo courtesy of Wikimedia Commons).

Synthetic Nucleic Acids Restore Normal Frataxin Levels in Patient-Derived Friedreich's Ataxia Cells

Neurological disease researchers have used synthetic nucleic acid polymers to block the defective FXN gene segment and restore normal levels of frataxin in cells derived from patients with Freidreich's ataxia.  More...
02 Mar 2016
Image: From left to right: Microscopic images comparing the hind leg muscles of normal mice, mice with spinal muscular atrophy, and mice with spinal muscular atrophy that have had the enzyme Jnk3 inhibited. Jnk3 deficiency appears to reduce muscle degeneration (muscle-wasting) and increase muscle growth in mice with the disease (Photo courtesy of the journal Human Molecular Genetics).

Search for Drugs to Treat Spinal Muscular Atrophy Pinpoints Likely Target Enzyme

Neurological disease researchers have identified a target for drugs to treat the hereditary childhood neurodegenerative disorder spinal muscular atrophy.  More...
02 Mar 2016
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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