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PURITAN MEDICAL

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Immunology

Image: The FACSAria III cell sorter (Photo courtesy of BD Biosciences).

Unconventional Cells Trigger Cytokine Production in Spondyloarthritis

Spondyloarthritides (SpA) refers to a cluster of inflammatory rheumatic diseases with a significant social-economic burden, affecting nearly 1% to 2% of the Western population. It is a complex disease with a diverse range of disease manifestations including spinal and peripheral joint inflammation. More...
22 Jan 2019
Image: A diagram of the role of CD69 in atherosclerosis (Photo courtesy of the Spanish National Center for Cardiovascular Research).

CD69 Biomarker Expression Predicts Atherosclerosis Risk

Atherosclerosis is a disease characterized by the accumulation of lipid deposits in the artery wall, but the disease is usually not detected until after it has caused a clinical event such as a myocardial infarction or stroke. More...
22 Jan 2019
DIASOURCE (A Biovendor Company)
Image: The Insti Multiplex HIV-1/HIV-2/Syphilis antibody test (Photo courtesy of bioLytical Laboratories).

Rapid Diagnostic Tests Evaluated for HIV/Syphilis

Sexually transmitted infections, such as human immunodeficiency virus (HIV) and syphilis, are among the major health care problems worldwide, especially in low- and middle-income countries. HIV screening programs have been widely used for many years. More...
22 Jan 2019
Image: The QuickPlex SQ120 utilizes MSD’s proprietary multi-array technology to provide significantly increased sensitivity and dynamic range over standard ELISA with the added benefit of multiplexing (Photo courtesy of Meso Scale Discovery).

Persistent Fatigue Induced by Interferon-Alpha

Chronic fatigue syndrome (CFS), or myalgic encephalomyelitis (ME), is a mysterious condition. The main symptom of CFS is extreme and often unrelenting fatigue; others include muscle and joint pain, sleep issues, and flu-like symptoms. More...
21 Jan 2019
Image: Photomicrograph of Acid-fast Ziehl-Neelsen Staining of Mycobacterium tuberculosis in a sputum smear (Photo courtesy of Rockefeller University).

Genetic Mutation Identified for TB Vulnerability

About one in five people worldwide are infected with Mycobacterium tuberculosis, the bacterium that causes tuberculosis. Of those, only 10%, at most, will show symptoms, because most immune systems have tools to fight the microbe. When these tools are absent or dysfunctional, however, the infection can damage the lungs and other organs, and even cause death. More...
15 Jan 2019
Image: The Calprolab enzyme-linked immunosorbent assay (ELISA ALP) test kit for calprotectin estimation (Photo courtesy of Calpro).

Calprotectin Independently Predicts Relapse in Treated RA

Calprotectin is a biomarker of disease activity in rheumatoid arthritis (RA) and psoriatic arthritis (PsA) and predicts relapse in juvenile idiopathic arthritis. Higher drug trough serum levels are associated with a good response in patients treated with tumor necrosis factor inhibitors (TNFi). More...
14 Jan 2019
Image: The BN II Nephelometer System is an easy-to-use, reliable nephelometric analyzer that offers a broad range of protein assays (Photo courtesy of Siemens Healthcare).

Urinary Biomarkers Associated with Kidney Disease Risk Factors

The improved life expectancy among treated human immunodeficiency virus (HIV)-positive patients has been tempered by the excess burden of age-related non-infectious co-morbidities, including chronic kidney disease (CKD). More...
14 Jan 2019
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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