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Hematology

Image: The Multiskan FC microplate photometer (Photo courtesy of Thermo Fisher Scientific).

Blood Test Helps Identify CV Patients Most at Risk

A new blood test could provide a clue as to why some patients are at higher risk of cardiovascular disease risk after suffering a heart attack, which may help scientists to identify new targets for reducing the risk and eventually lead to more effective treatments. More...
19 Feb 2018
Image: The MinION is the only portable real-time device for DNA and RNA sequencing (Photo courtesy of Oxford Nanopore Technologies).

Residual Disease in Leukemia Patients Identified by ddPCR

Currently, minimal residual disease for chronic myeloid leukemia (CML) patients is typically monitored using real-time quantitative polymerase chain reaction (RT-qPCR), but often leukemic stem cells with the BCR-ABL1 rearrangement are present below the limit of detect of RT-qPCR. More...
08 Feb 2018
Image: A blood draw using the PIVO device which allows patients to have blood taken multiple times during their hospital stay without having to undergo multiple needle sticks (Photo courtesy of Intermountain Healthcare).

New Blood Draw Device Evaluated For Hemolysis

Hemolysis, defined as the breakdown of red blood cells and the release of hemoglobin and intracellular contents into the plasma, is a frequent occurrence in blood samples submitted to clinical laboratories for testing.
 
 
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06 Feb 2018
Image: Acute lymphoblastic leukemia (Photo courtesy of Pathology Outlines).

Tumor Suppressor Gene Variants Identified for Leukemia Patients

Newly identified germline variations in a key tumor suppressor gene predispose individuals to develop leukemia as children and leave them with a 1-in-4 chance of developing a second cancer later. Acute lymphoblastic leukemia is the most common childhood cancer and in most cases, the exact cause is unknown. More...
16 Jan 2018
Image: Peripheral blood film from a newborn with hydrops fetalis; note the hypochromia, anisopoikilocytic changes, and erythroblastosis (Photo courtesy of Boston Medical Center).

Parental Screening Can Prevent Hydrops Fetalis in Fetus

Hydrops fetalis (fetal hydrops) is a serious fetal condition defined as abnormal accumulation of fluid in two or more fetal compartments, including ascites, pleural effusion, pericardial effusion, and skin edema. More...
10 Jan 2018
Image: The Star Evolution coagulation analyzer (Photo courtesy of Diagnostica Stago).

Drug Causes Missed Diagnosis of Protein S Deficiency

Rivaroxaban is a direct, antithrombin-independent factor Xa inhibitor, which inhibits not only free factor Xa, but also clot-bound factor Xa and the prothrombinase complex. It is used for treatment and prevention of venous thromboembolism, as well as for prophylaxis of stroke in patients with atrial fibrillation. More...
01 Jan 2018
Image: On the left side of the diagram, the ABL gene from Chromosome 9 and the BCR gene from Chromosome 22 are combined together to make the ‘Philadelphia chromosome’. This chromosome has a small part at the top and a longer part of the bottom. The bottom part is labelled as a fusion gene, which is BCR and ABL combined (Photo courtesy of Macmillan Cancer Support).

Digital PCR Test Monitors CML Therapy Response

Chronic myeloid leukemia, or CML, is characterized by the "Philadelphia chromosome," a translocation of chromosomes 9 and 22 that results in the breakpoint cluster region protein- Abelson murine leukemia viral oncogene homolog 1(BCR-ABL) gene fusion. More...
28 Dec 2017
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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