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Molecular Diagnostics

Image: The Karius test is a comprehensive next-generation sequencing (NGS) assay performed by the CLIA-certified and CAP-accredited Karius laboratory to identify and quantify microbial cell-free DNA in plasma from more than 1,000 bacteria, DNA viruses, fungi, molds, and protozoa (Photo courtesy of Karius).

Cell-Free DNA Sequencing Test for Infectious Disease Analyzed

A number of clinical collaborators testing a cell-free DNA sequencing test for infectious disease reported interim study results and anecdotal evidence of the assay. More...
22 Nov 2018
Image: A diagram of the KidCMP cohort of children with severe cardiomyopathies from the past 21 years who were analyzed genetically (Photo courtesy of Catalina Vasilescu/University of Helsinki).

Genetic Basis of Childhood-Onset Cardiomyopathies Identified

Personalized medicine is one of the goals of the current medical studies, where the understanding of the genetic cause and disease mechanism in each individual will promote tailored forms of treatment. Investigators make an important step in this direction by deciphering genetic causes in children and their implications for treatment decisions. More...
21 Nov 2018
Image: The QIAamp circulating nucleic acid kit (Photo courtesy of Qiagen).

Potential Brain Tumor Liquid Biopsies Developed

Liquid biopsies are fluid samples from patients, for example from the blood or urine, which provide a less invasive way to monitor disease compared to tumor biopsies. A less intrusive test could be hugely beneficial for brain tumors where collecting samples can be difficult and risky for patients. More...
20 Nov 2018
Image: The Idylla microsatellite instability (MSI) assay cartridge (Photo courtesy of Biocartis).

Microsatellite Instability Assay Validated for Cancer Studies

Microsatellite instability (MSI) occurs when mismatch repair proteins (MMR) fail to fix a DNA replication error, leading to frame-shift mutations in a person's genetic code and non-functioning proteins. MSI has acted as a strong marker for genetic conditions such as Lynch syndrome that can lead to a variety of cancers. More...
20 Nov 2018
Image: A diagram workflow of the ThyroSeq Genomic Classifier assay to determine preoperative thyroid cancer status (Photo courtesy of ThyroSeq).

Genetic Test Helps Patients Avoid Unnecessary Thyroid Surgery

A genetic test has been developed that can help avoid costly diagnostic surgery that involves removing one or both lobes of the thyroid gland, by reliably distinguishing between benign and cancerous thyroid nodules using a very small sample of cells. More...
19 Nov 2018
Image: The HSV2 ELITe MGB Kit is a real-time PCR assay designed for the detection and quantification of type 2 herpes simplex virus DNA (Photo courtesy of EliTech Group).

Herpes Simplex Virus Assay, Sample-to-Answer Instrument Get FDA Clearance

Herpes simplex virus 2 (HSV2) is a widespread herpes virus, usually sexually transmitted and responsible for genital herpes. Herpes simplex virus 1 (HSV1) is a common virus life-long established in the peripheral nervous system. More...
14 Nov 2018
Image: Immunostaining of breast cancer; distribution pattern of the Ki67 labeling index in breast cancer values (Photo courtesy of University of Szeged).

Breast Cancer Risk Variant Type Determines Tumor Aggressiveness

Interval breast cancer is a term for tumors detected within a year after a mammographic screening that was determined to be normal and is among the measures used to gauge the efficacy of breast screening programs. More...
14 Nov 2018
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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