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Clinical Chemistry

Image:Geographic distribution of the survey respondents. (Cavalier E, Kapoula G, Bhattoa HP, et al. IOF-IFCC international survey of global laboratory practices for bone status indices. Clin Chem Lab Med. 2026. DOI:10.1515/cclm-2026-0941.)

Global Survey Underscores Need to Standardize Bone Biomarker Testing

New data show variation across labs in bone marker testing, calling for harmonized reporting to improve clinical interpretation. More...
01 Oct 2026
Image: (a) CTC separation using contraction-expansion inertial microfluidics. (b) CTC detection using the YOLOv8 deep learning model. (Image Credit: Junyi Ouyang, Haiqin Li)

Label-Free Platform Combines Microfluidics and AI for Circulating Tumor Cell Analysis

A label-free platform combines microfluidic cell sorting with AI to enrich and identify rare circulating tumor cells. More...
01 Oct 2026
Image: The Innovance D‑Dimer 2.0 assay helps clinicians assess patients with suspected venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE) (Photo courtesy of Siemens Healthineers)

Rapid D-Dimer Assay Supports Exclusion and Monitoring of Serious Clotting Conditions

A new blood clotting test delivers rapid, highly specific results to help rule out DVT and PE, speeding emergency triage. More...
01 Oct 2026
Image Credit: 123RF

Noninvasive Earwax Test Aims to Detect Meniere’s Disease

A noninvasive earwax mass spectrometry approach enables objective detection of Meniere’s disease for screening and diagnosis. More...
30 Sep 2026
Image: The laser-based photoacoustic spectroscopy setup consists of a Mid-IR laser equipped with three QCL modules covering wavelengths from 5.6 μm to 12.9 μm, two silver coated mirrors (SCM), a dichroic mirror (DM) with a transmittance of 90%, a thermal power sensor head (PM) to monitor the output laser power, a mechanical chopper (MC) for frequency modulation and a CEPAS-detector with a self-designed swab holder (SH). (Credit: Graunke, T., Scholz, T., Pieniak, M. et al. Scientific Reports (2026). https://doi.org/10.1038/s41598-026-68298-9)

Laser-Based Swab Analysis Shows Promise for Detecting Disease-Linked Odor Patterns

New data show laser-based photoacoustic swabs distinguish healthy and disease odor patterns, pointing to simpler, faster analysis. More...
30 Sep 2026
Image: Researchers from the Department of Chemistry at Aarhus University have developed and tested a new technology that can identify and measure the concentration of pharmaceuticals in under 10 minutes. Today, this process takes up to an hour. That is critical waiting time for patients suffering from a stroke. (Image Credit: Aarhus University)

Point-of-Care Blood Test Could Speed Treatment Decisions in Acute Stroke

A new POC test rapidly quantifies anticoagulants in under 10 minutes, expediting stroke treatment decisions. More...
29 Sep 2026
Image: Antibody-coated microscopic beads are introduced into a tiny flow channel containing blood plasma. Laser irradiation enhances their interaction with CEACAM-5, a colorectal cancer biomarker, causing the beads to assemble and generate a detectable signal. (Image Credit: Figure reproduced from Iida et al., Nanoscale Horizons(2026), DOI: 10.1039/d6nh00017g. Licensed under CC BY-NC 4.0.)

Laser-Enhanced Assay Boosts Sensitivity for Colorectal Cancer Biomarker Detection

A laser-assisted microflow system detects a colorectal cancer biomarker in plasma within minutes. More...
29 Sep 2026
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The Clinical Chemistry channel updates the reader on tests, techniques, and research in the field - from routine assays to specialized tests on blood, urine, enzymes, lipids, hormones and more.
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