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BioResearch

Image: Osteoclast, with bone below it, shows typical distinguishing characteristics: a large cell with multiple nuclei and a “foamy” cytosol (Photo courtesy of Wikimedia Commons).

A MicroRNA Regulates the Mechanism That Prevents Osteoporosis and Bone Metastasis

A study conducted on a mouse model of osteoporosis found that animals with higher than normal levels of the microRNA miR-34a were protected from the syndrome by having increased bone mass and reduced bone breakdown.   More...
07 Jul 2014
Image: X-ray crystal structure of the NMDA receptor showing its mushroom-like shape, with receptor subunits in different colors (Photo courtesy of Oregon Health & Science University).

X-Ray Crystallography Offers First-Time 3D View of Vital Brain Receptor

Researchers have produced a new and extraordinary 3D view of one of the most important receptors in the brain—a receptor that allows humans to learn and remember, and whose malfunctioning is involved in a wide variety of neurologic disorders, including Alzheimer’s, Parkinson’s, depression, and schizophrenia.  More...
07 Jul 2014
Image: Space-filling model of the cholesterol molecule (Photo courtesy of Wikimedia Commons).

Cholesterol Inhibitor Blocks Breast Cancer Growth in Mouse Model

A low molecular weight drug that inhibits cholesterol biosynthesis was found to block the growth of breast tumors by modifying the ratio of proliferative and antiproliferative estrogen receptors.   More...
02 Jul 2014
Image: The muscle pacing method used in the study saw the rats gain 30% of bone within the targeted areas (Photo courtesy of the University of Liverpool).

Muscle-Pacing Technology Found to Increase Targeted Bone Volume by 30%

In an important advance, researchers have developed a new way to target bone growth.  More...
02 Jul 2014
Image: A three-dimensional rendering of clarified brain imaged from below (Photo courtesy of Deisseroth lab).

New Imaging Technology Provides Fly-Through Views of the Inner Brain Processes

Scientists have improved on an original technique for looking into the intact brain, making it more effective and safer. This new application could help scientists better determine the inner connections of how thoughts, memories, or diseases occur.  More...
02 Jul 2014

Cholesterol Metabolite Contributes to Buildup of Atherosclerotic Plaques

A recent paper described the mechanism by which the cholesterol metabolite 27-hydroxycholesterol contributes to the development of the fatty plaques that characterize atherosclerosis.  More...
01 Jul 2014
Image: An import protein coated molecule moving on the “dirty velcro” (Photo courtesy of Biozentrum, University of Basel).

Nanoscale Velcro Proteins Discovered to Be Used for Molecule Transport

Scientists have discovered that proteins found within the nuclear pore function similar to a “Velcro” snap that can be used for controlled and selective transport of particles.   More...
01 Jul 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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