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BioResearch

Image: Lawrence Livermore National Laboratory (LLNL) will develop an implantable neural device with the ability to record and stimulate neurons within the brain to help restore memory (Photo courtesy of DOE/Lawrence Livermore National Laboratory).

Research Lab to Develop World’s First Neural Device to Restore Memory

A USD 2.5 million grant has been awarded to a US research lab to develop an implantable neural device with the ability to record and stimulate neurons within the brain to help restore memory.  More...
04 Aug 2014

Loss of Endothelial Cell Enzyme Restores Sensitivity to Chemotherapy and Radiation in Nearby Tumor Cells

Cancer researchers have found that an enzyme produced by cells in the blood vessels that serve tumors triggers the release of signaling molecules that stimulate the repair of damage to the tumor cells caused by treatment with radiation or chemotherapeutic agents.  More...
04 Aug 2014
Image: XPro1595 is a clinical stage inhibitor of soluble TNFalpha (sTNF) for the treatment of neurodegenerative diseases including multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD). As a result of its unique mechanism of action, XPro1595 is positioned as not only for symptomatic treatment for these devastating diseases but as a disease modifying therapy as well (Photo  courtesy of FPRT Bio).

Experimental Drug Slows Progress of Parkinson's Disease in Rat Model

In a series of experiments designed to set the stage for future human clinical trials, an experimental anti-inflammatory drug was shown to prevent loss of dopamine-producing neurons and to reduce motor deficits in a rat model of Parkinson’s disease.  More...
04 Aug 2014
Image: Schematic of the intermediate structure in the aggregation pathway of amylin (Photo courtesy of Zhang, Buchanan, Zanni, Biomedical Spectroscopy and Imaging).

Two-Dimensional Infrared Spectroscopy Offers Clues into Amyloid Disease Mechanisms

New data revealed by using two-dimensional infrared spectroscopy shows an intermediate structure during the amylin aggregation pathway that may clarify toxicity, offering new strategies for interventions.   More...
04 Aug 2014

Precise Ion Irradiation Dosing Method Developed for Cancer Therapy

Scientists are employing nuclear physics principles to provide more effective approaches to radiotherapy treatment for cancer patients.   More...
31 Jul 2014
Image: In the liver tissue of obese animals with type II diabetes, unhealthy, fat-filled cells are prolific (small white cells, panel A). After chronic treatment through FGF1 injections, the liver cells successfully lose fat and absorb sugar from the bloodstream (small purple cells, panel B) and more closely resemble cells of normal, non-diabetic animals (Photo courtesy of the Salk Institute for Biological Studies).

Fibroblast Growth Factor 1 Treatment Restores Glucose Control in Mouse Diabetes Model

A "vaccine" based on the metabolic regulator fibroblast growth factor 1 removed the insulin resistance that characterizes type II diabetes and restored the body's natural ability to manage its glucose metabolism.  More...
31 Jul 2014
Image: A metabolic enzyme has an unexpected role in regulating gene expression in kidney cancer. Primary human kidney tissue: FBP1 protein (green); cell nuclei (blue) (Photo courtesy of the University of Pennsylvania).

Loss of Regulatory Enzyme Spurs Kidney Cancer Growth

Cancer researchers have found that the enzyme fructose-1,6-bisphosphatase 1 is missing or inactive in the clear cell renal cell carcinoma form of kidney cancer, a lack that gives the cancer cells a metabolic advantage over surrounding normal tissue.  More...
31 Jul 2014
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BioResearch brings the latest research news on the genome, proteome, metabolome, on drug discovery, and therapeutics. Biotech researchers, lab administrators, technologists, drug manufacturers, and suppliers can find the latest research news and information related to their fields of endeavor here.
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