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能准确检测宫颈癌的现代方法

By LabMedica International staff writers
Posted on 16 Sep 2014
更新颖的巴氏检验和人乳头瘤病毒(HPV)筛查能更准确地识别可能发展成宫颈癌的癌前细胞变化。

获得批准的新型液基巴氏检验筛查和检测宫颈癌及其前体能产生更好的结果,它使宫颈癌细胞更容易被看见,其检测率比传统的巴氏检验提高了64%以上。

美国新泽西州泽西市泽西海岸大学医疗中心正在开展一项临床实验,检测诱发宫颈癌的HPV菌株。宫颈癌妇女99%以上体内有HPV。实验证明基于DNA的新技术准确率比传统的巴氏检验高40%。检验患者液基巴氏样本中致癌的HPV菌株,以确定两种检验中是否有一种将提高癌症检测率或两者都将提高检测率。对参与实验妇女的要求是,至少21岁或以上,过去四个月没做过巴氏检验,也没接受过子宫切除术。

科学家使用的HPV筛查检验(BDS-USHPV)需要与碧迪诊断公司(Burlington, NC, USA)的BD Viper LT系统和BD SurePath液基巴氏检验配套使用。位于美国佐治亚州亚特兰大市的美国癌症学会预计,美国今年将有逾12,100名妇女将诊断出宫颈癌,大约4,220名妇女将死于宫颈癌。如果治疗得早,有效治疗和治愈宫颈癌的几率将骤增。

研究负责人Mark Martens大夫说:“数十年来妇女都是到她们的医生那里接受一年一次的巴氏检验,但FDA今年四月破天荒地批准用HPV检验取代巴氏检验。因为病人有了这一新选择,所以业界正在开发更多的检验方法,进一步拓宽女性的选择范围,我们也有幸参与其中开发这种更准确、更灵敏、更舒适的方法,以预防女性癌症。这项突破性的进展使我们社区的妇女享有当今最好的宫颈健康筛查。”

Related Links:
泽西海岸大学医疗中心
碧迪诊断公司
美国癌症学会


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