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Pathology

Image: Histopathology of Barrett\'s esophagus; the metaplasic epithelium of Barrett\'s esophagus is characterized by goblet cell, which stain blue with alcian blue (Photo courtesy of Nephron).

Molecular Test Predicts Cancer Risk of Barrett's Esophagus

A molecular diagnostic test has been developed for predicting risk of progression from Barrett's esophagus to esophageal cancer approximately three to four years before the cancer progresses.  More...
02 Jun 2015
Image: Histopathology of a prostate biopsy showing normal prostatic glands and glands of prostate cancer prostate adenocarcinoma in right upper aspect of image (Photo courtesy of Nephron).

Urine-Based Test Improves Detection of Prostate Cancer

A new urine-based test improved prostate cancer detection, including detecting more aggressive forms of prostate cancer, compared to traditional models based on prostate serum antigen, or PSA, levels.   More...
01 Jun 2015
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Microfluid Chip Traps Migrating Tumor Cell Clusters

A microfluidic chip has been developed that can capture rare clusters of circulating tumor cells, which could yield important new insights into how cancer spreads. More...
01 Jun 2015
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KRAS Mutation Test for Colorectal Cancer Diagnosis Approved

A real-time polymerase chain reaction test has been designed to identify the Kirsten rat sarcoma viral oncogene mutations in tumor samples from metastatic colorectal cancer patients and aid clinicians in determining a therapeutic path for them.  More...
27 May 2015
Image: Immunohistochemistry of stained estrogen receptor-positive breast cancer surgical pathology specimen (Photo courtesy of Dr. Ronald S. Weinstein, MD).

Second Pathology Analysis Ensures Proper Diagnosis and Treatment

A pathologic diagnosis is the foundation upon which all other treatment decisions are made with breast cancer and with the emergence of target therapy, the pathology dictates the use of potentially curable therapy.  More...
27 May 2015
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Small Molecule Detects Alzheimer's Disease at Early Stages

A high level of a small molecule called D-serine have been identified as associated with cognitive decline in Alzheimer’s disease and holds the potential to represent a novel and effective biomarker for AD.   More...
26 May 2015
Image: Histopathology of a spinal cord from an infant with multiple joint contractures present at birth (Photo courtesy of Dimitri P. Agamanolis, MD).

Infant Stiff-Joint Syndromes Matched to Possible Genetic Origins

There are over 400 specific disorders that are, or can be, associated with multiple contractures in the newborn and a better understanding of disorders with contractures and their associated genetics is critical for accurate diagnosis and optimal treatment.  More...
25 May 2015
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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