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Pathology

Image: The semi-quantitative Calprotectin 50 + 200 combo card test (Photo courtesy of CerTest Biotec).

Sensitive Clinical Marker Defined for Ulcerative Colitis Evolution

The two main subtypes of inflammatory bowel diseases (IBD), Crohn’s disease (CD) and ulcerative colitis (UC) are characterized by episodes of inflammatory activity and remission and determination of disease activity remains challenging, with most clinical scores correlating poorly with the inflammatory state. More...
20 Sep 2016
Image: A positive case of lung tissue detected by IHC-staining for anaplastic lymphoma kinase (ALK) with Ventana ALK (D5F3) CDx assay (Photo courtesy of Ventana).

Combined Use of Assays Identifies Cancer Patient Response to Crizotinib

In screening of a large cohort for anaplastic lymphoma kinase (ALK) fusions through both fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) assays, researchers found many non-small cell lung cancer (NSCLC) patients who had negative and atypical FISH patterns accompanied with positive IHC results, who showed response to crizotinib treatment. More...
19 Sep 2016
DIASOURCE (A Biovendor Company)
Image: The cantilever on the left bears the recognition sequence for the target mutation. If this is present in the sample being tested, the corresponding segment of RNA binds to the cantilever, causing the latter to bend. This can be measured, providing clear evidence that the genetic change is present (Photo courtesy of the University of Basel, Department of Physics).

Microcantilever-Based Sensor Detects BRAF-Mutated Malignant Melanoma

A novel nanosenor comprising minute cantilevers labeled with malignant melanoma-derived RNA enabled identification of patients with the BRAFV600E mutated form of the disease in less than 24 hours. More...
19 Sep 2016
Image: The BMG OPTIMA FLUOstar plate reader (Photo courtesy of BMG LABTECH).

Early Parkinson's Diagnosis Moves Closer with New Protein Test

There is currently no definitive test for Parkinson's and the disease is normally diagnosed through assessment of the patient's medical history, a medical examination, and physical and neurological tests, but this can take years. More...
15 Sep 2016
Image: The BD LSRII flow cytometer (Photo courtesy of Becton Dickinson).

Circulating Immune Cells Act As Idiopathic Pulmonary Fibrosis Biomarkers

Patients with fibrotic lung diseases, such as idiopathic pulmonary fibrosis (IPF), show progressive worsening of lung function with increased shortness of breath and dry cough. More...
14 Sep 2016
Image: The QX200 Droplet Digital Polymerase Chain reaction  (ddPCR) system (Photo courtesy of Bio-Rad).

Blood Test Detects New Breast Cancer Subtype

A blood test has been developed that detects when the most common form of breast cancer has become resistant to treatment could double the average time it takes for the disease to progress, from around two and a half to around six months. More...
14 Sep 2016
Image: Researchers have made a significant step towards the development of a simple blood test to predict the onset of Alzheimer’s disease (Photo courtesy of Cardiff University).

Proteins Predict Alzheimer's Disease Risk in Patients with Mild Cognitive Disorder

A blood test that measures a panel of three complement proteins was shown to predict which individuals with a mild cognitive disorder would most likely progress to develop Alzheimer's disease (AD). More...
12 Sep 2016
Gold Member
Quantitative POC Immunoassay Analyzer
EASY READER+
Serological Pipet Controller
PIPETBOY GENIUS
New
Silver Member
Quality Control Material
NATtrol Chlamydia trachomatis Positive Control
New
Anti-Thyroid Peroxidase Assay
LIAISON Anti-TPO


The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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