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Pathology

Image: A histopathology of squamous cell carcinoma of the esophagus (Photo courtesy of Nephron).

Age-Related Remodeling Linked to Normal Aging

Mutations in some cancer driver genes can arise in seemingly normal esophageal tissue as early as in childhood, becoming increasingly common with age and in response to alcohol or cigarettes. More...
21 Jan 2019
Image: A diagram showing normal and polycystic ovary syndrome, in the latter the ovaries may develop numerous small collections of fluid (follicles) and fail to regularly release eggs (Photo courtesy of Mayo Clinic).

New Risk Loci Identified for Polycystic Ovary Syndrome

Polycystic ovary syndrome is a disorder characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have metabolic disturbances including insulin resistance and dysregulation of glucose homeostasis. More...
09 Jan 2019
Image: The FLUOstar Omega is a multi-mode microplate reader and has six detection modes (Photo courtesy of BMG LabTech).

Test Detects Protein Associated with Alzheimer’s and CTE

An ultrasensitive test has been developed that detects a corrupted protein associated with Alzheimer’s disease and chronic traumatic encephalopathy (CTE). This advance could lead to early diagnosis of these conditions and how they originate. More...
09 Jan 2019
Image: The NovaSeq 6000 sequencing system platform (Photo courtesy of Illumina).

Diverse Chronic Kidney Diseases Diagnosed with Exome Sequencing

Exome sequencing is emerging as a first-line diagnostic method in some clinical disciplines, but its usefulness has yet to be examined for most constitutional disorders in adults, including chronic kidney disease, which affects more than 1 in 10 persons globally. More...
08 Jan 2019
Image: A comparison of OncoScan array CGH assay–derived metastasis potential scores (MPSs) for indolent primary tumor (iPT) and metastasis-prone primary tumor (mPT) samples (Photo courtesy of Albert Einstein College of Medicine).

Rapid Next-Gen Sequencing Method Predicts Prostate Cancer Risks

Prostate cancer is the most commonly diagnosed male cancer and the second leading cause of cancer deaths among men in the USA, with approximately 220,000 new diagnoses and approximately 27,000 deaths each year. More...
08 Jan 2019
Image: Genome-wide human SNP array 6.0 GeneChip (Photo courtesy of Affymetrix).

Metastatic Colorectal Cancer Linked to Transcription Factors

Colorectal cancer (CRC) is a kind of malignant human tumor with high mortality around the world. The incidence of colorectal cancer shows a gender difference and is prone to the elderly. More...
03 Jan 2019
Image: A new screening method for cervical cancer has proven 100% accurate in testing (Photo courtesy of Health News).

Epigenetic Cervical Cancer Test Has Perfect Detection Rate

Human papillomavirus (HPV) ‐based cervical cancer screening requires triage of HPV positive women to identify those at risk of cervical intraepithelial neoplasia grade 2 (CIN2) or worse. More...
02 Jan 2019
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The Pathology channel details advances in the field of Surgical Pathology and all its subspecialties, including Cytopathology and its subspecialties.
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