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Immunology

Image: The BEP 2000 Advance System fully automated microtitration plate (MTP) analyzer (Photo courtesy of Siemens).

Test Predicts Death in Patients with Serious Liver Disease

Acute-on-chronic liver failure is a sudden deterioration of the liver function in a patient with liver cirrhosis accompanied by failure of one or more organ systems and this liver disease has a serious prognosis and the four-week mortality rate is 20% to 30%.  More...
12 Apr 2016
Image: Schematics of the combination of Amotosalen and UVA illumination for eliminating pathogens from donor blood for transfusions (Magdy El Ekiaby, MD).

Zika Virus Inactivated in Plasma for Transfusion

The potential for Zika virus transmission through blood transfusion has been demonstrated during the French Polynesian outbreak as 2.8% of blood donors, who were asymptomatic at the time of donation, were found positive for acute ZIKV infection using specific reverse transcription–polymerase chain reaction.   More...
03 Apr 2016
DIASOURCE (A Biovendor Company)
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Noninvasive Method Determines Subclinical Childhood Celiac Disease

A new, simple and noninvasive method has been developed to determine whether a child aged two to four years of age suffers from celiac disease or not, without the necessity of a blood extraction. Silent celiac disease goes unnoticed to the eyes of the doctor because it presents minor symptoms, imperceptible even for the patient.   More...
29 Mar 2016
Image: The geographic distribution of Japanese encephalitis (in red) (Photo courtesy of the CDC – US Centers for Disease Control and Prevention).

Dried Cerebrospinal Fluid Spots Detect Anti-Japanese Encephalitis IgM

The use of filter paper as a simple, inexpensive tool for storage and transportation of blood, “Dried Blood Spots” or Guthrie cards, for diagnostic assays is well-established, but in contrast, there are a paucity of diagnostic evaluations of dried cerebrospinal fluid spots.  More...
29 Mar 2016
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Immune Cells Adapt Inefficiently in Patients with Uncontrolled HIV

Antibodies derived from a type of immune cell found in unusually high numbers in human immunodeficiency virus-infected individuals with chronically uncontrolled virus levels are less effective at neutralizing HIV than antibodies derived from a different type of immune cell more common in people without HIV.  More...
28 Mar 2016
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Immunoassay Systems Evaluated for Detection of Antiphospholipid Antibodies

Antiphospholipid syndrome or antiphospholipid antibody syndrome, or also Hughes syndrome, is an autoimmune, hypercoagulable state caused by antiphospholipid antibodies.  More...
28 Mar 2016
Image: The Videssa Breast diagnostic test provides accurate early detection and typing of breast cancers by combining anatomical evidence from imaging with evidence from its proteomics test for proteins released into the blood system by cancer tumors (Image courtesy of Provista Diagnostics).

Age Should Be Considered in Developing Diagnostic Assays

In a new study on breast cancer, blood test results have demonstrated age-related differences in Tumor-Associated Antibodies, showing for the first time age-related differences that should be taken into consideration when developing diagnostic tests.  More...
23 Mar 2016
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The Immunology channel of LabMedica deals with diagnostic techniques and immuonassays such as ELISA, pregnancy tests, immunoblotting, immunohistochemical staining, serology, and associated hardware.
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