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Hematology

Image: Platelet granules in a blood sample stained for the marker protein CD63 visualized by Structured Illumination Microscopy (Photo courtesy of the University College London).

Super-Resolution Microscopy Improves Platelet Granule Disorder Diagnosis

Platelets or thrombocytes form part of the blood, help heal wounds, and prevent bleeding by forming blood clots and they do this through tiny granules that release molecules for blood clotting.   More...
15 Feb 2016
Image: Peripheral blood smear of a patient with acute myeloid leukemia (Photo courtesy of Dr. Abbas H. Abdulsalam).

Blood Test Improves Treatment for Acute Myeloid Leukemia

A simple blood test has been developed that is capable of detecting trace levels of leukemia cells remaining after intensive chemotherapy. The test can predict which patients with acute myeloid leukemia are at risk of their cancer returning in the future, helping to guide doctors on what further treatment is needed.   More...
10 Feb 2016
Image: Sporangiophores, columellae and primitive rhizoids of Rhizomucor spp., the zygomycetous fungus detected by the PathoChip, which has the ability to detect all known viruses, as well as a variety of bacteria, fungi, helminths, and protozoa (Photo courtesy of the University of Adelaide).

Fungal Infection Identified by Pathogen Detection Array Technology

Patients who are undergoing treatment for diseases such as cancer often face the added challenge of a compromised immune system, which can be challenging to both of their condition and the drugs used to treat it, leaving them vulnerable to various opportunistic infections.  More...
09 Feb 2016
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Nonradioactive Serotonin Release Assay Compared to Gold Standard

The serotonin release assay is considered the gold standard laboratory test for heparin-induced thrombocytopenia and the classical SRA method uses platelets loaded with radiolabeled serotonin to evaluate platelet activation by HIT immune complexes.  More...
01 Feb 2016
Image: Bone marrow aspirate of acute myeloid leukemia: Azurophilic granularity can be seen in essentially all of the blasts and variability in nuclear size and contour is observable (Photo courtesy of Dr. John Lazarchick, MD).

Early and Accurate Prediction of Leukemia Made Possible

Acute myeloid leukemia is the most common type of leukemia in adults and recent studies demonstrate that early and accurate prediction of this aggressive cancer is possible how it will develop in individuals.  More...
25 Jan 2016
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Key Genes Identified for Leukemia Development

Human leukemia is characterized by the prevalence of recurrent chromosomal translocations, resulting in the generation of chimeric fusion proteins with aberrant oncogenic activities.   More...
25 Jan 2016
Image: Novel hemostasis monitoring microdevice comprises a microfluidic mechanism with hollow channels through which blood is flowed and a proprietary algorithm for analyzing patient-specific data to predict when blood clots will form (Photo courtesy of Wyss Institute).

Microfluidic Device Automatically Monitors Whole Blood Hemostasis

An assay has been devised for testing blood's clotting tendency, also known as hemostasis, which could one day prove lifesaving in a variety of clinical situations in which a patient's health is jeopardized by abnormal blood coagulation and platelet function.  More...
20 Jan 2016
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The Hematology channel at LabMedica covers the all aspect of plasma, coagulation, transfusion medicine, and blood banking, as well as related lab tools and techniques.
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