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Molecular Diagnostics

Image: The BioMek FXP automation workstation (Photo courtesy of Beckman Coulter).

Innovative Gene Testing Technology Finds Cancer Risks

A new method has been developed for identifying mutations and prioritizing variants in breast and ovarian cancer genes, which will not only reduce the number of possible variants for doctors to investigate, but also increase the number of patients that are properly diagnosed. More...
19 May 2016
Image: The Xpert HPV assay is a qualitative real-time polymerase chain reaction (qRT-PCR) test for automated and rapid detection of Human Papillomaviruses (Photo courtesy of Cepheid).

HPV Infection Identified In Self-Collected Vaginal Swabs

High risk, potentially cancer causing human papillomavirus infections (HPV) are common among women in the developing world, but self-sampling with vaginal swabs may provide materials that screen as accurately as the more labor-intensive approach using cervical samples obtained by clinicians. More...
19 May 2016
Image: The handheld device that can detect Ebola Virus Ribonucleic Acid (Photo courtesy of KIST Europe).

Palm-Sized Device Quickly Detects Ebola Virus

The gold standard method for identifying the Ebola virus in a blood sample requires packaging samples in cooled containers and sending them to specialized laboratories, often far away from where patients live. More...
18 May 2016
Image: A photomicrograph of an abnormal Pap smear showing changes consistent with Human Papilloma Virus (HPV) and Mild Dysplasia. Note the irregular perinuclear cytoplasmic clearing, which is the key characteristic of identifying HPV visually on a Pap smear (Photo courtesy of Dr. Cynthia D Booth, MD).

Combining Two Diagnostic Tests Drastically Reduces Cancer Miss Rates

The Papanicolaou (Pap) test is recommended for women between 21 and 65 years old as a screening test for cervical cancer. Women 30 and older who are negative on co-testing may wait as long as five years for their next testing, but physicians still recommend annual examinations. More...
17 May 2016
Image: A black cartridge containing the innovative paper-based diagnostic for detecting Zika virus: areas that have turned purple indicate samples infected with Zika virus, while yellow areas indicate Zika-free samples (Photo courtesy of Wyss Institute at Harvard University).

CRISPR-based Technology Enables High-Resolution Zika Detection On Low-Cost Paper Discs

Building off their earlier innovative development in “programmable diagnostics”, researchers on an international, multi-institutional team recently joined efforts to quickly prototype their low-cost rapid test with the goal that it could soon be used to screen samples (blood, urine, or saliva) for Zika virus and strain identification. More...
16 May 2016
Image: The MassARRAY Dx analyzer system (Photo courtesy of Agena Bioscience).

Diagnostic Tests For Lung And Colon Cancer Launched In Europe

A unique combination of reliability, sensitivity, ease of use, and cost-effectiveness for targeted genetic testing for cancer has now become available to molecular pathologists. More...
12 May 2016
Image: A histopathology of prostate cancer showing multiple poorly formed glands with ill-defined lumina and/or incomplete nuclear complement, Gleason score 3+4 = 7 (Photo courtesy of European Urology).

Non-Invasive Prostate Cancer Test Developed Using Exosomal RNA

The current screening paradigm for prostate cancer faces challenges that lead to unnecessary biopsies and, ultimately, overtreatment. The disadvantage of Prostate-Specific Antigen (PSA) testing is lack of specificity for prostate cancer resulting in both false positive and false negative results. More...
11 May 2016
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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