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Molecular Diagnostics

Image: A whole-mount section of the prostate from a cystoprostatectomy specimen with extension of the urothelial carcinoma of the bladder to the prostate (arrows). The encircled area is an incidental prostatic carcinoma (Photo courtesy of European Urology).

Biomarker of Aggressive Prostate Cancer Discovered

The level of a specific molecule present in prostate tumors is an indicator of whether the cancer is aggressive and likely to spread and this will aid future clinical tests to help doctors decide how best to treat prostate tumors. More...
18 Aug 2016
Image: Sequins are small stretches of synthetic DNA to be added as a standardization control to a DNA sample during sequencing, helping analyze the large data files generated for genomic analysis. The technology is based on the notion of mirror image DNA. Sequins are essentially “mirror” images of natural DNA sequences. They behave like natural DNA sequences but can be easily recognized as synthetic (Photo courtesy of Chris Hammang, Garvan Institute of Medical Research).

Sequins As Novel Internal Controls to Improve Genomic Analysis

Researchers have developed an intuitive technology called “Sequins” – synthetic “mirror” DNA sequences that reflect the human genome and can be used to better map, navigate, and analyze complexity within the genome. Currently human genome Sequins are freely available for research. More...
16 Aug 2016
Image: A histopathology of the colon with multiple Adenomatous polyps (Photo courtesy of Group14).

Novel Gene Discovered for Hereditary Colon Cancer

The formation of large numbers of polyps in the colon has a high probability of developing into colon cancer, if left untreated. The large-scale appearance of polyps is often due to a hereditary cause; in this case the disease can occur in multiple family members. More...
08 Aug 2016
Image: An immunohistochemistry analysis of BRCA1 performed on normal tissue and human ovary carcinoma tissue (Photo courtesy of the CDC).

Gene Testing Simplified for Women with Ovarian Cancer

A new streamlined approach to genetic testing for women with ovarian cancer provides testing rapidly and affordably, allowing many more patients to benefit from personalized cancer management and their relatives to benefit from cancer prevention strategies. More...
04 Aug 2016
Image: The Aperio Scanscope CS whole slide scanner system (Photo courtesy of Leica).

Gene Panel Predicts Damage in Donated Kidneys

Kidney transplantation is a life-extending procedure and a panel of genes has been identified that can help predict whether a transplanted kidney will later develop fibrosis, an injury which can cause the organ to fail. More...
04 Aug 2016
Image: The SurePath preservative fluid kit (Photo courtesy of Becton Dickinson and Company).

HPV Test Approved for Use with SurePath Preservative Fluid

Human papilloma virus (HPV) infections are the most common sexually transmitted infections in the USA, and HPV genotypes 16 and 18 cause approximately 70 % of cervical cancers worldwide. According to the National Cancer Institute, there will be an estimated 12,990 new cases and 4,120 deaths from cervical cancer in the USA during 2016. More...
03 Aug 2016
Image: The SepsiTest allows the reliable molecular analysis of whole blood samples for bacteremia and fungemia (Photo courtesy of Molzym).

Direct Molecular Detection of Bloodstream Infection Evaluated

Blood culture is the current gold standard for detecting bacteria in blood, requires at least 24 to 48 hours and has limited sensitivity if obtained during antibiotic treatment of the patient. Severe sepsis is sepsis associated with organ dysfunction, hypoperfusion, or hypotension. More...
02 Aug 2016
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Genetic Testing channel of LabMedica brings the latest in molecular genetics, cytogenetics, and epigenetics, and methods from PCR to FISH, and more.
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